CD2 Antibody (299812) [Allophycocyanin]

Human peripheral blood lymphocytes were stained with Mouse Anti-Human CD2 APC‑conjugated Monoclonal Antibody (Catalog # FAB18561A, filled histogram) or isotype control antibody (Catalog # IC002A, open histogram). View our protocol for Staining Membrane-associated Proteins.

• Reactivity: Hu
• Applications: Flow
• Clone: 299812
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Allophycocyanin

CD2 Antibody (299812) [Allophycocyanin] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human CD2
  Lys25-Asp209
  Accession # P06729
• Specificity: Detects recombinant human CD2 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant mouse (rm) CD2 or rmCD2F-10 is observed.
• Source: N/A
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: CD2
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 10 uL/10^6 cells

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
• Buffer: Supplied in a saline solution containing BSA and Sodium Azide.
• Preservative: Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CD2 Antibody (299812) [Allophycocyanin]

• CD2 antigen (p50), sheep red blood cell receptor
• CD2 antigen
• CD2 molecule
• CD2
• Erythrocyte receptor
• FLJ46032
• LFA-2
• LFA-3 receptor
• lymphocyte-function antigen-2
• Rosette receptor
• SRBC
• T11
• T-cell surface antigen CD2
• T-cell surface antigen T11/Leu-5

Background

CD2 is a type I glycoprotein belonging to the Ig superfamily and is expressed on T, NK, B, and some antigen presenting cells. Human CD2 binds human CD58 on antigen-presenting cells to induce co-stimulating signals in T cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for CD2 Antibody (FAB18561A)(1)

Publication using FAB18561A

• Justin S. A. Perry, Emilie V. Russler-Germain, You W. Zhou, Whitney Purtha, Matthew L. Cooper, Jaebok Choi et al. Scavenger receptor CD36 mediates cell-surface antigen transfer to promote thymic regulatory T cell receptor repertoire development and allo-tolerance Immunity 2018-05-08 [PMID: 29752065]

Bioinformatics

• Gene Symbol: CD2
• Uniprot:
  • P06729()