CD1b Antibody (737249) [Alexa Fluor™ Plus 488]

• Reactivity: Hu
• Clone: 737249
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 488

CD1b Antibody (737249) [Alexa Fluor™ Plus 488] Summary

• Specificity: Detects human CD1b in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) CD1a, rhCD1c, rhCD1d, rhCD1e, recombinant mouse (rm) CD1d1, or rmCD1d2 is observed.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CD1b Antibody (737249) [Alexa Fluor™ Plus 488]

• CD1
• CD1A
• CD1b antigen
• CD1B antigen, b polypeptide
• CD1b molecule
• CD1b
• cortical thymocyte antigen CD1B
• differentiation antigen CD1-alpha-3
• MGC125990
• MGC125991
• R1
• T-cell surface glycoprotein CD1b

Background

CD1b is an approximately 40-50 kDa transmembrane glycoprotein in the CD1 family of glycolipid antigen-presenting MHC-like molecules. CD1b associates with beta 2-microglobulin in endosomes and the Golgi where it facilitates the processing of glycolipids for their presentation by other CD1 family proteins. CD1b is expressed by most nonhuman mammals but not by mice or rats. It contains one Ig-like domain in its extracellular region. Alternate splicing of human CD1b generates an additional isoform that lacks 55 amino acids of the Ig-like domain.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.