CD161/NK1.1 Antibody (694370) [Alexa Fluor® 594]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow
Clone
694370
Clonality
Monoclonal
Host
Rat
Conjugate
Alexa Fluor 594
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.

CD161/NK1.1 Antibody (694370) [Alexa Fluor® 594] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse CD161/NK1.1
Val62-Ser220
Accession # P27814
Specificity
Detects mouse CD161/NK1.1 expressed specifically in the C57/B6 mouse strain. No detection of  CD161/NK1.1 was observed in the BALB/c mouse strain. In direct ELISAs, less than 5% cross-reactivity with recombinant mouse (rm) KLRB-1B is observed.
Isotype
IgG2a
Clonality
Monoclonal
Host
Rat
Gene
KLRB1C
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 0.25-1 ug/10^6 cells
Application Notes
Flow Cytometry: Please use 0.25-1 ug of conjugated antibody per 10e6 cells.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Buffer
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Preservative
0.09% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CD161/NK1.1 Antibody (694370) [Alexa Fluor® 594]

  • CD161 antigen
  • CD161
  • CD161/NK1.1
  • CD161c
  • CLEC5BC-type lectin domain family 5 member B
  • HNKR-P1a
  • killer cell lectin-like receptor subfamily B member 1
  • killer cell lectin-like receptor subfamily B, member 1
  • Klrb1c
  • Ly55c
  • Ly-59
  • Natural killer cell surface protein P1A
  • NKR-P1
  • NKR-P1AMGC138614
  • NKRP1ANKR

Background

KLRB1C, also known as NK1.1, CD161c, Ly-55, and NKR-P1c, is a 28 kDa type 2 transmembrane protein in the killer cell lectin-like receptor family. CD161 is expressed as a disulfide-linked homodimer on the surface of NK cells and subpopulations of NKT, CD4+, CD8+, and gamma /δ T cells. Its cross-linking on NK cells induces cytolytic activity, and on CD4 cells it promotes IgE production and the expansion of Th2 responses. Mature mouse CD161 consists of a 45 amino acid (aa) cytoplasmic domain, a 21 aa transmembrane segment, and a 157 aa extracellular domain with one C-type lectin domain.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 FAB7614U
Alexa Fluor 405 FAB7614V
Alexa Fluor 488 FAB7614G
Alexa Fluor 594 FAB7614T
Alexa Fluor 647 FAB7614R
Alexa Fluor 700 FAB7614N
Alexa Fluor 750 FAB7614S

Additional CD161/NK1.1 Products

Array FAB7614T

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Diseases for CD161/NK1.1 Antibody (FAB7614T)

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Bioinformatics

Gene Symbol KLRB1C
Uniprot