HEK293 human embryonic kidney cell line transfected with rat CCR2 and eGFP was stained with either (A) Mouse Anti-Rat CCR2 PE‑conjugated Monoclonal Antibody (Catalog # FAB8368P) or (B) Mouse IgG2B Phycoerythrin ...read more
12 months from date of receipt, 2 to 8 °C as supplied.
Supplied in a saline solution containing BSA and Sodium Azide.
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for CCR2 Antibody (890231) [Phycoerythrin]
C-C chemokine receptor type 2
chemokine (C-C motif) receptor 2
Monocyte chemoattractant protein 1 receptor
monocyte chemotactic protein 1 receptor
CCR2, also known as CD192, is a 38 kDa 7TM chemokine
receptor that preferentially binds CCL2, CCL7, and CCL13. CCR2 is expressed by
multiple hematopoietic cells, endothelial cells, fibroblasts, neurons, and
smooth muscle cells. It functions as an HIV fusion co-factor and facilitates T
cell recruitment during inflammation. Two alternate splice forms (CCR2A and
CCR2B) differ only by the addition of 14 amino acids to the intracellular
carboxyl terminal. Rat CCR2 shares 95% aa sequence identity with mouse CCR2.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
CCR2 or CD192 CCR2 is a receptor for several monocyte chemoattractant proteins (MCP1, MCP3, MCP4) that specifically govern monocyte chemotaxis. CCR2 transduces its downstream signals through increasing intracellular calcium ion levels. For example, MCP1 regulate... Read full blog post.
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