CCL2/MCP1 Antibody [DyLight 650] Summary
Synthetic peptide made to an internal portion of rat MCP1 (within residues 15-40). [Swiss-Prot# P14844]
Secreted, secretory vesicles
Immunogen affinity purified
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Packaging, Storage & Formulations
Store at 4C in the dark.
DyLight 650 (A=652, E=672)
50mM Sodium Borate
0.05% Sodium Azide
Please see the vial label for concentration. If unlisted please contact technical services.
Immunogen affinity purified
This MCP1 antibody is useful for Immunocytochemistry/Immunofluorescence and Western blot, where a band is seen at ~16 kDa. In ICC/IP secretory vesicles staining was observed in HeLa cells.
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.
Alternate Names for CCL2/MCP1 Antibody [DyLight 650]
- C-C motif chemokine 2
- chemokine (C-C motif) ligand 2
- HC11Monocyte secretory protein JE
- MCAFMonocyte chemotactic and activating factor
- MCP1 Monocyte chemotactic protein 1
- MCP-1 Small-inducible cytokine A2
- Monocyte chemoattractant protein 1
- monocyte chemoattractant protein-1
- small inducible cytokine A2 (monocyte chemotactic protein 1, homologous tomouse Sig-je)
- small inducible cytokine subfamily A (Cys-Cys), member 2
Rat MCP-1 (monocyte chemoattracctant protein-1) is a 148-amino acid CC chemokine with a NH2-terminal sequence of 29 residues as a signal sequence. This rat MCP-1/JE is 49-amino acid longer than human MCP-1 at 3-end. This 3-end is a serine and threonine rich zone, which is probably responsible for the extensive O-glycosylation. MCP-1 is produced by a wide range of cell types as a reaction to diverse inflammatory stimuli and is a chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. MCP-1 augments monocyte anti-tumor activity and has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. In atherosclerosis MCP-1 may has been implicated to be involved in the recruitment of monocytes into the arterial wall during the disease process.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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