CCL2/MCP1 Antibody (ECE.2)

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB, IA, IHC, IHC-Fr
Clone
ECE.2
Clonality
Monoclonal
Host
Rat
Conjugate
Unconjugated
Concentration
0.1 mg/ml

Order Details

CCL2/MCP1 Antibody (ECE.2) Summary

Immunogen
The antibody reacts with murine JE / MCP-1.
Isotype
IgG1
Clonality
Monoclonal
Host
Rat
Gene
CCL2
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • Immunoassay
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen
Application Notes
The antibody is useful for detection of MCP-1 by Western blot. Furthermore it can be used in immunoassays. The typical starting working dilution is 1:10. It is recommended that users test the reagent and determine their own optimal dilutions. Although not tested this antibody may be useful in immunohistochemistry on frozen and paraffin sections. Use in Immunohistochemistry-Frozen reported in scientific literature (PMID: 26413869)
Publications
Read Publications using
NBP1-42312 in the following applications:

  • IHC
    2 publications
  • WB
    1 publication

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS containing 0.1% BSA
Preservative
0.02% Sodium Azide
Concentration
0.1 mg/ml
Purity
Protein A or G purified

Alternate Names for CCL2/MCP1 Antibody (ECE.2)

  • C-C motif chemokine 2
  • chemokine (C-C motif) ligand 2
  • GDCF-2
  • HC11Monocyte secretory protein JE
  • MCAFMonocyte chemotactic and activating factor
  • MCP1 Monocyte chemotactic protein 1
  • MCP-1 Small-inducible cytokine A2
  • MGC9434
  • Monocyte chemoattractant protein 1
  • monocyte chemoattractant protein-1
  • SCYA2HSMCR30
  • small inducible cytokine A2 (monocyte chemotactic protein 1, homologous tomouse Sig-je)
  • small inducible cytokine subfamily A (Cys-Cys), member 2
  • SMC-CF

Background

Monocyte chemoattractant protein-1 (MCP-1) is a member of the chemokine-beta family of cytokines. The protein is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. It may play a inprotant role in the initiation and/or progression of pulmonary hypertension (PH). Blockade of a systemic MCP-1 signal pathway in vivo may prevent PH.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for CCL2/MCP1 Antibody (NBP1-42312)(3)

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for CCL2/MCP1 Antibody (NBP1-42312)

Discover related pathways, diseases and genes to CCL2/MCP1 Antibody (NBP1-42312). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Blogs on CCL2/MCP1.

MCP-1 - chemoattractant protein involed in monocyte migration and infiltration
Monocyte chemotractant protein-1 (MCP-1), also known as CCL2, is a key chemokine involved in the migration of monocytes and macrophages to sites of active inflammation. It is a member of the C-C/beta family of cytokines, characterized by the Cys-C...  Read full blog post.

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Bioinformatics

Gene Symbol CCL2