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CCL2/MCP1 Antibody (2H5)

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Summary
Product Discontinued
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    • Catalog Number
      NB100-78196
    • Availability
      Product Discontinued

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CCL2/MCP1 Antibody (2H5) Summary

Immunogen
CHO-expressed, recombinant mouse MCP-1
Specificity
MCP-1 (2H5)
Isotype
IgG
Clonality
Monoclonal
Host
Armenian Hamster
Gene
CCL2
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • ELISA 5-10 ug/ml
  • Immunocytochemistry/ Immunofluorescence 0.5 ug/10^6 cells in 100 ul
Application Notes
Additional reported applications include: Western blotting and Immunohistochemistry of paraformaldehyde-fixed, saponin-treated frozen tissue sections.
Publications
Read Publication using
NB100-78196 in the following applications:

Reactivity Notes

Rhesus Monkey

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS (pH 7.2)
Preservative
0.09% Sodium Azide
Concentration
0.5 mg/ml
Purity
Protein A or G purified

Alternate Names for CCL2/MCP1 Antibody (2H5)

  • C-C motif chemokine 2
  • chemokine (C-C motif) ligand 2
  • GDCF-2
  • HC11Monocyte secretory protein JE
  • MCAFMonocyte chemotactic and activating factor
  • MCP1 Monocyte chemotactic protein 1
  • MCP-1 Small-inducible cytokine A2
  • MGC9434
  • Monocyte chemoattractant protein 1
  • monocyte chemoattractant protein-1
  • SCYA2HSMCR30
  • small inducible cytokine A2 (monocyte chemotactic protein 1, homologous tomouse Sig-je)
  • small inducible cytokine subfamily A (Cys-Cys), member 2
  • SMC-CF

Background

Monocyte chemotactic protein-1 (MCP-1) also known as monocyte chemotactic and activating factor (MCAF) was identified based on its ability to chemoattract monocytes. Subsequently, MCP-1 has also been found to regulate adhesion molecule expression and cytokine production in monocytes. MCP-1 is identical to the product of the JE gene, a PDGF inducible gene. MCP-1 is a member of the beta (C-C) chemokine subfamily, known as CCL2. The 2H5 antibody reacts with mouse, rat, and human MCP-1. The 2H5 antibody can neutralize the bioactivity of natural or recombinant MCP-1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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CCL2/MCP1 Antibody
(2H5)
NB100-78196
CCL2/MCP1 Antibody (2H5)
Species: Hu, Mu, Rt
Applications: ELISA, ICC/IF

Publications for CCL2/MCP1 Antibody (NB100-78196)(1)

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 1 application: IF/IHC.


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IF/IHC
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MCP-1 - chemoattractant protein involed in monocyte migration and infiltration
Monocyte chemotractant protein-1 (MCP-1), also known as CCL2, is a key chemokine involved in the migration of monocytes and macrophages to sites of active inflammation. It is a member of the C-C/beta family of cytokines, characterized by the Cys-C...  Read full blog post.

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Bioinformatics

Gene Symbol CCL2
Entrez
Uniprot