CBL 293T Cell Transient Overexpression Lysate

Product Discontinued

CBL 293T Cell Transient Overexpression Lysate Summary

• Description: Quality control test: Transient overexpression cell lysate was tested with Anti-CBL antibody by Western Blots. Plasmid: pCMV-CBL full-length
• Specificity: CBL 293T Cell Transient Overexpression Lysate(Denatured)
• Gene: CBL

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Store at -80C. Avoid freeze-thaw cycles.
• Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)

Lysate Details for Array

• Type: 293T Cell Transient Overexpression
• Protein State: Denatured

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for CBL 293T Cell Transient Overexpression Lysate

• Cas-Br-M (murine) ecotropic retroviral transforming sequence
• Casitas B-lineage lymphoma proto-oncogene
• CBL
• CBL2
• CBL2E3 ubiquitin-protein ligase CBL
• EC 6.3.2
• EC 6.3.2.-
• oncogene CBL2
• Proto-oncogene c-Cbl
• RING finger protein 55
• RNF55
• RNF55C-CBL
• Signal transduction protein CBL

Background

c-Cbl, product of c-cbl proto-oncogene, is a 120 kDa cytoplasmic protein involved in tyrosine kinase-dependent signaling pathways (1-3). c-Cbl is one of the earliest targets of tyrosine phosphorylation in response to a number of cellular stimuli. For instance, stimulation of growth factor receptors by EGF, PDGF, NGF and FGF, results in c-Cbl tyrosine phosphorylation, in lymphoid and other cell lines (4).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Lysates are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: CBL