Cathepsin H Antibody (175909) [DyLight 650]

• Reactivity: Mu
• Applications: WB
• Clone: 175909
• Clonality: Monoclonal
• Host: Rat
• Conjugate: DyLight 650

Cathepsin H Antibody (175909) [DyLight 650] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse Cathepsin H
  Glu22-Val333
  Accession # Q3UCD6
• Specificity: Detects mouse Cathepsin H in direct ELISAs and Western blots. It recognizes both the pro and active forms of recombinant mouse (rm) Cathepsin H. In Western blots, no cross-reactivity with rmCathepsin A, D, E, X, and Z or recombinant human Cathepsin B, C, L, or S is observed.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Rat
• Gene: CTSH
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Cathepsin H Antibody (175909) [DyLight 650]

• ACC-4
• ACC-5
• aleurain
• cathepsin B3
• cathepsin BA
• Cathepsin H
• CPSB
• CTSH
• DKFZp686B24257
• EC 3.4.22
• EC 3.4.22.16
• MGC1519
• minichain
• N-benzoylarginine-beta-naphthylamide hydrolase

Background

Cathepsin H is encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. The encoded protein, which belongs to the peptidase C1 protein family, can act both as an aminopeptidase and as an endopeptidase. Increased expression of this gene has been correlated with malignant progression of prostate tumors. Two transcript variants encoding different isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CTSH