Species: Hu
Applications: AC
Description
Cathepsin H is a lysosomal glycoprotein and a member of the cysteine proteinase. This cysteine protease class comprises cathepsin B, H, K, L, and O. These proteinases are viewed as simple mediators of lysosomal protein degradation. Cathepsin H is synthesized as an inactive proenzyme (41 kDa) and then proteolytically processed to an active single chain, mature form (28 kDa) within the endosomes/lysosomes. This proteinase is a peptidehydrolase that firstly isolated from rat liver, and then identified in liver, kidney, spleen, and brain of different mammals. Furthermore, cathepsin H is increased in disease states including breast carcinoma, melanoma, gliomas, and colorectal and prostate carcinoma.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
|
| Product By Gene ID |
1512 |
| Alternate Names |
- ACC-4
- ACC-5
- aleurain
- cathepsin B3
- cathepsin BA
- Cathepsin H
- CPSB
- CTSH
- DKFZp686B24257
- EC 3.4.22
- EC 3.4.22.16
- MGC1519
- minichain
- N-benzoylarginine-beta-naphthylamide hydrolase
|
Research Areas for Cathepsin H
Find related products by research area and learn more about each of the different research areas below.
Cancer
