Human Cathepsin C/DPPI ELISA Kit (Colorimetric)

ELISA: Human Cathepsin C/DPPI ELISA Kit (Colorimetric) [NBP3-00372] - Samples were spiked with high concentrations of Human Cathepsin C/DPPI and diluted with Reference Standard & Sample Diluent to produce samples with values within the range of the assay.

ELISA: Human Cathepsin C/DPPI ELISA Kit (Colorimetric) [NBP3-00372] - Standard Curve Reference

• Reactivity: Hu
• Applications: ELISA
• Suitable Sample Type: Serum, plasma, cell supernatant, and other biological fluids
• Standard Curve Range: 0.31 - 20 ng/mL
• Sensitivity: 0.19 ng/mL

Human Cathepsin C/DPPI ELISA Kit (Colorimetric) Summary

• Specificity: This kit recognizes Human Cathepsin C/DPPI in samples. No significant cross-reactivity or interference between Human Cathepsin C/DPPI and analogues was observed.
• Standard Curve Range: 0.31 - 20 ng/mL
• Sensitivity: 0.19 ng/mL
• Assay Type: Sandwich-ELISA
• Inter-Assay: 5.04%
• Intra-Assay: 4.87%
• Spike Recovery: 86 - 104%
• Sample Volume: 100 ul
• Kit Type: ELISA Kit (Colorimetric)
• Gene: CTSC

Applications/Dilutions

• Dilutions:
  • ELISA

Packaging, Storage & Formulations

• Storage: Storage of components varies. See protocol for specific instructions.

Alternate Names for Human Cathepsin C/DPPI ELISA Kit (Colorimetric)

• Cathepsin C
• cathepsin CEC 3.4.14.1
• Cathepsin J
• CPPIHMS
• CTSC
• dipeptidyl peptidase 1
• Dipeptidyl peptidase I
• Dipeptidyl transferase
• dipeptidyl-peptidase I
• DPP1
• DPPI
• DPP-I
• JP
• JPD
• PALS
• PLS

Background

DPP1 is encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor, and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: CTSC