Caspase-8 Antibody (90A992) [DyLight 488]


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Product Details

Reactivity Hu, PmSpecies Glossary
Applications WB, Flow, IHC-P
Please see the vial label for concentration. If unlisted please contact technical services.

Caspase-8 Antibody (90A992) [DyLight 488] Summary

The immunogen for this product falls between amino acids 360-385 of the human Caspase 8 protein.
This can be used for detection of the pro-form of Caspase-8.
Protein G purified
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Packaging, Storage & Formulations

Store at 4C in the dark.
DyLight 488
DyLight 488 (A=493, E=518)
50mM Sodium Borate
0.05% Sodium Azide
Protein G purified


  • Western Blot
  • Flow Cytometry 1ul/1 million cells
  • Immunohistochemistry-Paraffin

Reactivity Notes

Chimpanzee and Rhesus Monkey.


Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Caspase-8 Antibody (90A992) [DyLight 488]

  • AIS
  • androgen receptor
  • CASP8
  • Caspase8
  • Dihydrotestosterone receptorHYSP1
  • Mch5
  • NR3C4KD
  • Nuclear receptor subfamily 3 group C member 4
  • spinal and bulbar muscular atrophy


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for Caspase-8 Antibody (NB100-56527G). (Showing 1 - 1 of 1 FAQ).

  1. May we ask the MW difference between the active form and the proform of Caspase 8 while performing WB?
    • In treated cells induced to undergo apoptosis, caspase-8 migrates as a 55/53 kDa (pro-form), 41/42 kDa (a cleaved/active or intermediate form), and 18 kDa (active form). The proform (55/53 kDa) is still seen in treated cells because not all cells undergo apoptosis at once.

Secondary Antibodies


Isotype Controls

Other Available Formats

Allophycocyanin Labeled NB100-56527APC
Biotin Labeled NB100-55786
DyLight 350 Labeled NB100-56527UV
DyLight 405 Labeled NB100-56527V
DyLight 405LS Labeled NB100-56527V3
DyLight 550 Labeled NB100-56527R
DyLight 650 Labeled NB100-56527C
DyLight 680 Labeled NB100-56527FR
DyLight 755 Labeled NB100-56527IR
HRP Labeled NB100-56527H
PE Labeled NB100-56527PE
PerCP Labeled NB100-56527PCP

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Blogs on Caspase-8.

Caspase 3, the executioner of apoptosis
Caspase-3 enzyme is a member of the family of endoproteases which regulate inflammation and apoptosis signaling networks. Caspase-3 is known as an executioner caspase in apoptosis because of its role in coordinating the destruction of cellular stru...  Read full blog post.

VPS41 - An important regulator of lysosomal trafficking
Membrane fusion is an essential step during the trafficking of endosomes and vesicles throughout the cell. Membrane fusion events are facilitated by multisubunit tethering complexes (MTC) including CORVET and HOPS. These complexes interact with Rab...  Read full blog post.

Caspase-8 - a pro-apoptotic protein with dynamic roles in normal physiology and pathology
Caspases are a family of cysteine-aspartic acid proteases that are responsible for the initiation and execution of apoptosis. Caspase-8 is a 55 kDa protein expressed as an inactive procaspase that resides in the cytosol. Activation of Caspase-8 req...  Read full blog post.

Caspase 8 - a key mediator of apoptosis
Programmed cell death via apoptosis is a key controlled physiological process instigated by the cell death receptor family, their ligands, and the caspase cysteine protease family. All caspases exist in a precursor form that contains a prodomain, a...  Read full blog post.

Contact Information

Product PDFs


Gene Symbol CASP8

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