Carboxypeptidase E/CPE Antibody

Images

 
Western Blot: Carboxypeptidase E/CPE Antibody [NBP2-15699] - Analysis of CPE expression in transfected 293T cell line by CPE polyclonal antibody. A: Non-transfected lysate. B: CPE transfected lysate. 12% SDS PAGE gel, ...read more
Immunohistochemistry-Paraffin: Carboxypeptidase E/CPE Antibody [NBP2-15699] - Paraffin-embedded breast cancer. Carboxypeptidase E antibody [N2C2], Internal dilution: 1:500.
Western Blot: Carboxypeptidase E/CPE Antibody [NBP2-15699] - Sample (20 ug of whole cell lysate) A: mouse brain 10% SDS PAGE gel, diluted at 1:10000.

Product Details

Summary
Reactivity Hu, Mu, Rt, Po, Bv, Pm, RMSpecies Glossary
Applications WB, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.68 mg/ml

Order Details

Carboxypeptidase E/CPE Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human Carboxypeptidase E. The exact sequence is proprietary.
Localization
Secreted
Predicted Species
Rat (96%), Porcine (95%), Bovine (94%), Rhesus Macaque (99%), Primate (99%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CPE
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:10000
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
Theoretical MW
53 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Chimpanzee (99%), Zebrafish (85%), Xenopus laevis (83%).

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris (pH 7.0), 0.1M Glycine and 10% Glycerol
Preservative
0.01% Thimerosal
Concentration
0.68 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Carboxypeptidase E/CPE Antibody

  • Carboxypeptidase E
  • Carboxypeptidase H
  • CPE
  • CPH
  • CPH-1
  • EC 3.4.17
  • EC 3.4.17.10
  • Enkephalin convertase
  • Prohormone-processing carboxypeptidase

Background

This gene encodes a carboxypeptidase that cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. It is a peripheral membrane protein. The protein specifically binds regulated secretory pathway proteins, including prohormones, but not constitutively secreted proteins. Mutations in this gene are implicated in type II diabetes. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CPE
Entrez
Uniprot