Carboxypeptidase B2/CPB2 Antibody (OTI3D5) - Azide and BSA Free

Immunohistochemistry: Carboxypeptidase B2/CPB2 Antibody (OTI3D5) - Azide and BSA Free [NBP2-70444] - Analysis of Carcinoma of Human lung tissue. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min)

• Reactivity: Hu
• Applications: IHC
• Clone: OTI3D5
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free
• Concentration: LYOPH

Carboxypeptidase B2/CPB2 Antibody (OTI3D5) - Azide and BSA Free Summary

• Description: Novus Biologicals Mouse Carboxypeptidase B2/CPB2 Antibody (OTI3D5) - Azide and BSA Free (NBP2-46345) is a monoclonal antibody validated for use in IHC. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Human recombinant protein fragment corresponding to amino acids 224-423 of human CPB2(NP_001863) produced in E.coli.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: CPB2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:150
  • Immunohistochemistry-Paraffin
• Theoretical MW: 45.9 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Lyophilized from PBS (pH 7.3) with 8% Trehalose
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: Immunogen affinity purified
• Reconstitution Instructions: we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process.

Alternate Names for Carboxypeptidase B2/CPB2 Antibody (OTI3D5) - Azide and BSA Free

• carboxypeptidase B2 (plasma)
• carboxypeptidase B2 (plasma, carboxypeptidase U)
• Carboxypeptidase B2
• Carboxypeptidase U
• CPB2
• CPU
• CPUEC 3.4.17.20
• EC 3.4.17
• PCPB
• Plasma carboxypeptidase B
• TAFI
• TAFIcarboxypeptidase B-like protein
• Thrombin-activable fibrinolysis inhibitor
• thrombin-activatable fibrinolysis inhibitor

Background

Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). The protein encoded by this gene is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for this gene and its promoter region. Available sequence data analyses indicate splice variants that encode different isoforms. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CPB2