Carboxypeptidase B2/CPB2 Products

Description

Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). The protein encoded by this gene is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for this gene and its promoter region. Available sequence data analyses indicate splice variants that encode different isoforms. [provided by RefSeq]

Bioinformatics

Entrez	1361 Human
Uniprot	AAH07057 Human NP_001863 Human NP_001863.2 Human Q96IY4 Human
Product By Gene ID	1361
Alternate Names	carboxypeptidase B2 (plasma) carboxypeptidase B2 (plasma, carboxypeptidase U) carboxypeptidase B2 Carboxypeptidase U CPUEC 3.4.17.20 EC 3.4.17 PCPB pCPB Plasma carboxypeptidase B TAFIcarboxypeptidase B-like protein Thrombin-activable fibrinolysis inhibitor thrombin-activatable fibrinolysis inhibitor