Canine IL-1 beta/IL-1F2 DuoSet ELISA, 15 Plate

• Reactivity: Ca
• Applications: ELISA
• Conjugate: Biotin

Canine IL-1 beta/IL-1F2 DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: IL1B

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Canine IL-1 beta/IL-1F2 DuoSet ELISA, 15 Plate

• Catabolin
• IL1 beta
• IL-1 beta
• IL-1
• IL1B
• IL-1b
• IL1-BETA
• IL-1F2
• IL1F2IL-1 beta
• interleukin 1, beta
• interleukin-1 beta
• preinterleukin 1 beta
• pro-interleukin-1-beta

Background

IL-1 beta (Interleukin-1 beta) is produced in response to inflammatory agents, infections, or microbial endotoxins. It plays a central role in immune and inflammatory responses, bone remodeling, fever, carbohydrate metabolism, and GH/IGF-I physiology. IL-1 beta dysregulation is implicated in many pathological conditions including sepsis, rheumatoid arthritis, inflammatory bowel disease, acute and chronic myelogenous leukemia, insulin-dependent diabetes mellitus, atherosclerosis, neuronal injury, and aging-related diseases. Intracellular cleavage of the IL-1 beta precursor by Caspase-1/ICE is a key step in the inflammatory response. IL-1 beta binds to IL-1 RI and IL-1 RII. The IL-1 receptor accessory protein (IL-1 RAcP) associates with IL-1 RI and is required for IL-1 RI signal transduction, and IL-1ra is a secreted molecule that functions as a competitive inhibitor of IL-1 bioactivity.

Publications for IL-1 beta/IL-1F2 (DY3747)(8)

Publications using DY3747

• Jung, K;Ku, JY;Kwon, JS;Won, G;Yoon, H;Oh, SI;Kim, MH;Kim, C;Yoon, JS; IFN-?/TNF-? Synergism Induces Pro-Inflammatory Cytokine and Chemokine Production by In Vitro Canine Keratinocytes Veterinary sciences 2025-01-14 [PMID: 39852930] (Canine)
• Costa, SF;Soares, MF;Poleto Bragato, J;Dos Santos, MO;Rebech, GT;de Freitas, JH;de Lima, VMF; MicroRNA-194 regulates parasitic load and IL-1?-dependent nitric oxide production in the peripheral blood mononuclear cells of dogs with leishmaniasis PLoS neglected tropical diseases 2024-01-01 [PMID: 38241360] (Canine)
• GT Rebech, JP Bragato, SF Costa, JH de Freitas, MO Dos Santos, MF Soares, FR Eugênio, PSP Dos Santos, VMF de Lima miR-148a regulation interferes in inflammatory cytokine and parasitic load in canine leishmaniasis PloS Neglected Tropical Diseases, 2023-01-31;17(1):e0011039. 2023-01-31 [PMID: 36719867] (Canine)
• S Kim, YS Hyun, HT Park, MK Shin, HS Yoo Mycobacterium intracellulare induces a Th17 immune response via M1-like macrophage polarization in canine peripheral blood mononuclear cells Scientific Reports, 2022-07-12;12(1):11818. 2022-07-12 [PMID: 35821058] (Canine)
• JC Alves, A Santos, P Jorge, C Lavrador, LM Carreira Effect of a single intra-articular administration of stanozolol in a naturally occurring canine osteoarthritis model: a randomised trial Scientific Reports, 2022-04-07;12(1):5887. 2022-04-07 [PMID: 35393497] (Canine)
• Z Digby, P Tourlomous, J Rooney, JP Boyle, B Bibo-Verdu, RJ Pickering, SJ Webster, TP Monie, LJ Hopkins, N Kayagaki, GS Salvesen, S Warming, L Weinert, CE Bryant Evolutionary loss of inflammasomes in the Carnivora and implications for the carriage of zoonotic infections Cell Reports, 2021-08-24;36(8):109614. 2021-08-24 [PMID: 34433041] (Canine)
• JC Alves, A Santos, P Jorge, C Lavrador, LM Carreira The intra-articular administration of triamcinolone hexacetonide in the treatment of osteoarthritis. Its effects in a naturally occurring canine osteoarthritis model PLoS ONE, 2021-01-20;16(1):e0245553. 2021-01-20 [PMID: 33471857] (Canine)
• T Ichiki, BK Huntley, GJ Harty, SJ Sangaralin, JC Burnett Early activation of deleterious molecular pathways in the kidney in experimental heart failure with atrial remodeling Physiol Rep, 2017-05-15;5(9):. 2017-05-15 [PMID: 28507167] (Canine)

FAQs for IL-1 beta/IL-1F2 (DY3747). (Showing 1 - 1 of 1 FAQs).

1. wondering what the difference is between your quantikine and duo set elisas?
   • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Bioinformatics

• Gene Symbol: IL1B