CAMP/LL37/FALL39/Cathelicidin Antibody (OSX12)

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Immunocytochemistry/ Immunofluorescence: CAMP/LL37/FALL39/Cathelicidin Antibody (OSX12) [NBP1-46781] - Staining of a cytospin preparation of peripheral blood mononuclear cells (PBMC) isolated from buffycoat. Cells were ...read more
Immunocytochemistry/ Immunofluorescence: CAMP/LL37/FALL39/Cathelicidin Antibody (OSX12) [NBP1-46781] - Staining of a cytospin preparation of peripheral blood mononuclear cells (PBMC) isolated from buffycoat. Cells were ...read more
Immunocytochemistry/ Immunofluorescence: CAMP/LL37/FALL39/Cathelicidin Antibody (OSX12) [NBP1-46781] - Staining on ethanol-fixed human spermatosoid using Mouse monoclonal to human Cathelicidin (CAP-18, antibacterial ...read more
Immunocytochemistry/ Immunofluorescence: CAMP/LL37/FALL39/Cathelicidin Antibody (OSX12) [NBP1-46781] - Staining on ethanol-fixed human spermatosoid using Mouse monoclonal to human Cathelicidin (CAP-18, antibacterial ...read more
Immunocytochemistry/ Immunofluorescence: CAMP/LL37/FALL39/Cathelicidin Antibody (OSX12) [NBP1-46781] - Staining on ethanol-fixed human spermatosoid using Mouse monoclonal to human Cathelicidin (CAP-18, antibacterial ...read more
Immunocytochemistry/ Immunofluorescence: CAMP/LL37/FALL39/Cathelicidin Antibody (OSX12) [NBP1-46781] - Staining on ethanol-fixed human spermatosoid using Mouse monoclonal to human Cathelicidin (CAP-18, antibacterial ...read more
Immunocytochemistry/ Immunofluorescence: CAMP/LL37/FALL39/Cathelicidin Antibody (OSX12) [NBP1-46781] - Staining of a cytospin preparation of peripheral blood mononuclear cells (PBMC) isolated from buffycoat. Cells were ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow, ICC/IF, IHC, IHC-P, IP
Clone
OSX12
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

CAMP/LL37/FALL39/Cathelicidin Antibody (OSX12) Summary

Immunogen
A synthetic peptide from human Cathelicidin antimicrobial peptide (CAP-18, hCAP-18, antibacterial protein LL-37, CAMP, CRAMP, FALL39) conjugated to an immunogenic carrier protein has been used as the immunogen.
Specificity
Specific for Cathelicidin antimicrobial peptide.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
CAMP
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 5-10 ug/ml
  • Flow Cytometry 5-10 ug/ml
  • Immunocytochemistry/Immunofluorescence 5-10 ug/ml
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 5-10 ug/ml
  • Immunoprecipitation
Application Notes
Immunohistochemistry-paraffin, IF, Western Blot, flow cytometry. Use at a concentration of 5-10 ug/ml. The optimal concentration should be determined by the end user. Although not tested this antibody may be useful in Immunohistochemistry-frozen. Use in immoprecipitation reported in scientific literature (PMID 26508735)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
No buffer
Preservative
No Preservative
Purity
Protein A or G purified
Reconstitution Instructions
Please note the larger size(s) come in lyophilized form and the sample size will be in liquid formate. Reconstitute with 0.1 ml sterilized water.

Alternate Names for CAMP/LL37/FALL39/Cathelicidin Antibody (OSX12)

  • 18 kDa cationic antimicrobial protein
  • CAMP
  • CAMP/LL37
  • CAP18
  • CAP18CRAMP
  • cathelicidin antimicrobial peptide
  • CRAMP
  • FALL39
  • FALL-39
  • FALL39CAP-18
  • hCAP-18
  • LL37

Background

Cathelicidins are a family of antimicrobial proteins predominantly found in the peroxidase negative granules of neutrophils. The cathelicidins are synthesized as preproproteins. Within the neutrophils, they are stored in granules as inactive proforms after removal of the signal peptide. The active biologic domains of the cathelicidins generally reside in the C terminus. The C terminal antimicrobial peptides are activated when cleaved from the proforms of the cathelicidins by serine proteases from azurophil granules.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for CAMP/LL37/FALL39/Cathelicidin Antibody (NBP1-46781). (Showing 1 - 1 of 1 FAQ).

  1. I would like to get a technical information about your antibody Cathelicidin Antibody (OSX12), product-number NBP1-46781. Does this antibody recognize specifically the C-terminal antimicrobial domain LL-37, which is liberated by proteinase 3 from cathelicidin?
    • A synthetic peptide from human Cathelicidin antimicrobial peptide (LL-37) conjugated to an immunogenic carrier protein was used as the immunogen to generate our Cathelicidin antibody with catalogue number NBP1-46781. The peptide immunogen was derived from the C-terminus of the protein, however the exact length and amino acid sequence is proprietary and I am, unfortunately, unable to disclose it.

Secondary Antibodies

 

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Bioinformatics

Gene Symbol CAMP
Entrez
Uniprot