Recombinant Human CaMKIV His Protein

Recombinant Human CaMKIV Protein [NBP1-78878]

• Reactivity: Hu
• Applications: IP, PAGE
• Concentration: 0.5 mg/ml

Recombinant Human CaMKIV His Protein Summary

• Description: A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-473 of Human CaMKIV
  
  

  Source: E.coli

  Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMLKVTV PSCSASSCSS VTASAAPGTA SLVPDYWIDG SNRDALSDFF EVESELGRGA TSIVYRCKQK GTQKPYALKV LKKTVDKKIV RTEIGVLLRL SHPNIIKLKE IFETPTEISL VLELVTGGEL FDRIVEKGYY SERDAADAVK QILEAVAYLH ENGIVHRDLK PENLLYATPA PDAPLKIADF GLSKIVEHQV LMKTVCGTPG YCAPEILRGC AYGPEVDMWS VGIITYILLC GFEPFYDERG DQFMFRRILN CEYYFISPWW DEVSLNAKDL VRKLIVLDPK KRLTTFQALQ HPWVTGKAAN FVHMDTAQKK LQEFNARRKL KAAVKAVVAS SRLGSASSSH GSIQESHKAS RDPSPIQDGN EDMKAIPEGE KIQGDGAQAA VKGAQAELMK VQALEKVKGA DINAEEAPKM VPKAVEDGIK VADLELEEGL AEEKLKTVEE AAAPREGQGS SAVGFEVPQQ DVILPEY

• Source: E. coli
• Protein/Peptide Type: Recombinant Protein
• Gene: CAMK4
• Purity: >85%, by SDS-PAGE

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • SDS-Page
• Application Notes: Use in IP reported in scientific literature (PMID:34506942).
• Theoretical MW: 54.5 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20 mM Tris-HCl buffer (pH8.0), 10% glycerol, 0.1 M NaCl
• Preservative: No Preservative
• Concentration: 0.5 mg/ml
• Purity: >85%, by SDS-PAGE

Alternate Names for Recombinant Human CaMKIV His Protein

• brain Ca(2+)-calmodulin-dependent protein kinase type IV
• brain Ca++-calmodulin-dependent protein kinase type IV
• calcium/calmodulin-dependent protein kinase IV
• calcium/calmodulin-dependent protein kinase type IV catalytic chain
• calcium/calmodulin-dependent protein kinase type IV
• CAM kinase- GR
• CAM kinase IV
• CaM kinase-GR
• CaMK IV
• caMK
• CaMK-GR
• EC 2.7.11
• EC 2.7.11.17
• IV
• MGC36771

Background

CAMK4 belongs to the serine/threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This enzyme is a multifunctional serine/threonine protein kinase with limited tissue distribution, that has been implicated in transcriptional regulation in lymphocytes, neurons and male germ cells. Recombinant human CAMK4 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Publications for CaMKIV Recombinant Protein (NBP1-78878)(1)

Publication using NBP1-78878

• MEvel E, Shutter JA, Ding X et al. Systemic inhibition or global deletion of CaMKK2 protects against post-traumatic osteoarthritis Osteoarthritis and cartilage 2021-09-17 [PMID: 34506942] (IP)

Bioinformatics

• Gene Symbol: CAMK4