Calponin 1 Antibody (CNN1/832) [DyLight 405]

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Product Details

Summary
Reactivity Hu, RtSpecies Glossary
Applications Flow, IHC, IHC-P
Clone
CNN1/832
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 405

Order Details

Calponin 1 Antibody (CNN1/832) [DyLight 405] Summary

Immunogen
Recombinant human CNN1 protein
Localization
Cytoplasmic
Marker
Smooth Muscle Marker
Specificity
Multiple isoelectric variants of calponin have been identified, however only two molecular weight isoforms exist; a 34kDa form and a 29kDa form. Expression of the 29kDa form, I-calponin, is primarily restricted to muscle of the urogenital tract, whereas the higher molecular weight variant has been demonstrated in vascular and visceral smooth muscle. In Western blotting, this MAb reacts with only the 34kDa form of calponin in extracts of human aortic medial smooth muscle and is unreactive with fibroblast extracts of cultivated human foreskin. Calponin is a calmodulin, F-actin and tropomyosin binding protein, which is thought to be involved in the regulation of smooth muscle contraction. Calponin expression is restricted to smooth muscle cells and has been shown to be a marker of the differentiated (contractile) phenotype of developing smooth muscle.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
CNN1
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Calponin 1 Antibody (CNN1/832) [DyLight 405]

  • Basic calponin
  • Calponin 1
  • calponin 1, basic, smooth muscle
  • Calponin H1
  • Calponin H1, smooth muscle
  • calponins, basic
  • CNN1
  • Sm-Calp
  • SMCC
  • SMCCcalponin-1

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-47757AF350
Alexa Fluor 405 NBP2-47757AF405
Alexa Fluor 488 NBP2-47757AF488
Alexa Fluor 532 NBP2-47757AF532
Alexa Fluor 594 NBP2-47757AF594
Alexa Fluor 647 NBP2-47757AF647
Alexa Fluor 700 NBP2-47757AF700
Alexa Fluor 750 NBP2-47757AF750
Allophycocyanin NBP2-47757APC
Biotin NBP2-47757B
DyLight 350 NBP2-47757UV
DyLight 405 NBP2-47757V
DyLight 488 NBP2-47757G
DyLight 550 NBP2-47757R
DyLight 594 NBP2-47757DL594
DyLight 650 NBP2-47757C
DyLight 680 NBP2-47757FR
DyLight 755 NBP2-47757IR
FITC NBP2-47757F
HRP NBP2-47757H
Janelia Fluor 549 NBP2-47757JF549
Janelia Fluor 646 NBP2-47757JF646
PE NBP2-47757PE
PerCP NBP2-47757PCP

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Contact Information

Learn the difference between western blot and simple western

Product PDFs

Calculators

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Bioinformatics

Gene Symbol CNN1