Applications: WB, IHC, ICC
Host: Mouse Monoclonal
Species: Hu, Mu, Rt, Mouse, Rat
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Applications: IHC, ICC
Host: Sheep Polyclonal
Applications: RNAi, RNAi SP
Calponin is a smooth muscle specific, actin-, tropomyosin- and calmodulin-binding protein thought to be involved in regulation of actomyosin as well as the regulation or modulation of contraction (1). Calponin binds filamentous actin (F-actin) through two distinct sites ABS1 and ABS2, with an affinity in the low micromolar range (2) Immunoreactivity for calponin, along with alpha-smooth muscle actin and smooth muscle myosin heavy chains, confirms the known neoplastic myoepithelial component of adenoid cystic carcinomas and epithelial-myoepithelial carcinomas. The consistently positive staining pattern in adenoid cystic carcinomas may be diagnostically useful in discriminating histologically similar but consistently negative polymorphous low-grade adenocarcinomas (3).
Research Areas for Calponin 1
Find related products by research area and learn more about each of the different research areas below.CancerCytoskeleton Markers
PTMs for Calponin 1
Learn more about PTMs related to Calponin 1.Phosphorylation
Bioinformatics Tool for Calponin 1
Discover related pathways, diseases and genes to Calponin 1. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.