Caldesmon/CALD1 Antibody (CALD1/820 + h-CALD) [DyLight 755]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, IHC, IHC-P, ICC/IF
Clone
CALD1/820 + h-CALD
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 755

Caldesmon/CALD1 Antibody (CALD1/820 + h-CALD) [DyLight 755] Summary

Immunogen
Recombinant full-length human CALD1 protein (CALD1/820); Crude human uterus extract (h-CALD)
Localization
Cytoplasmic
Marker
Smooth Muscle Marker
Specificity
Recognizes a protein of 150kDa, which is identified as the high molecular weight variant of Caldesmon. Two closely related variants of human caldesmon have been identified which are different in their electrophoretic mobility and cellular distribution. The h-caldesmon variant (120-150kDa) is predominantly expressed in smooth muscle whereas l-caldesmon (70-80kDa) is found in non- muscle tissue and cells. Neither of the two variants has been detected in skeletal muscle. This MAb recognizes only the 150kDa variant (h-caldesmon) in Western blots of human aortic media extracts and is unreactive with fibroblast extracts from cultivated human foreskin. Caldesmon is a developmentally regulated protein involved in smooth muscle and non-muscle contraction.
Isotype
IgG
Clonality
Monoclonal
Host
Mouse
Gene
CALD1
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Immunofluorescence
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Alternate Names for Caldesmon/CALD1 Antibody (CALD1/820 + h-CALD) [DyLight 755]

  • CAD
  • CALD1
  • caldesmon 1
  • Caldesmon
  • CDM
  • CDMH-CAD
  • HCAD
  • LCAD
  • L-CAD
  • MGC21352
  • NAG22

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics Tool for Caldesmon/CALD1 Antibody (NBP2-47819IR)

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Bioinformatics

Gene Symbol CALD1