CA15-3 Antibody (DBMM1)

Immunohistochemistry-Paraffin: CA15-3 Antibody (DBMM1) [NBP2-26672] - Formalin fixed paraffin embedded, stained with CA15-3 Antibody (NBP2-26672).

• Reactivity: Hu
• Applications: IHC
• Clone: DBMM1
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated

CA15-3 Antibody (DBMM1) Summary

• Description: Novus Biologicals Mouse CA15-3 Antibody (DBMM1) (NBP2-26672) is a monoclonal antibody validated for use in IHC. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Human breast cancer cell line ZR-75-1
• Localization: Cytoplasmic, cell membrane
• Specificity: This antibody is specific to epithelial membrane antigen (EMA), CA15-3, or polymorphic epithelial mucin. This antibody stains an underglycosylated MUC1 often present on carcinoma cells.
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Purity: Tissue culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:50-1:100
  • Immunohistochemistry-Paraffin 1:50-1:100
• Application Notes: IHC-P: recommended pretreatment of EDTA buffer, pH 8.0. Recommended incubation time of 30 min at RT.

Reactivity Notes

Human

Packaging, Storage & Formulations

• Storage: Store at 4C.
• Buffer: Tissue culture supernatant
• Preservative: 0.05% Sodium Azide
• Purity: Tissue culture supernatant

Alternate Names for CA15-3 Antibody (DBMM1)

• ADMCKD1
• ADMCKD2
• ADTKD2
• Breast carcinoma-associated antigen DF3
• CA153
• CA15-3
• Cancer antigen 15-3
• Carcinoma-associated mucin
• CD227
• EMA
• episialin
• H23 antigen
• H23AG
• KL-6
• Krebs von den Lungen-6
• MAM6
• MCD
• MCKD
• MCKD1
• MUC1
• MUC-1
• MUC-1/SEC
• MUC-1/X
• MUC1/ZD
• mucin 1, transmembrane
• Peanut-reactive urinary mucin
• PEM
• PEMT
• Polymorphic epithelial mucin
• PUM
• tumor associated epithelial mucin
• Tumor-associated epithelial membrane antigen

Background

This antibody is specific to epithelial membrane antigen (EMA), CA 15-3, or polymorphic epithelial mucin. This antibody stains an underglycosylated MUC1 often present on carcinoma cells. DF3 antigen present on the apical borders of secretory mammary epithelial cells. It stains glandular epithelia of breast, colon, kidney, liver, lung, pancreas, salivary gland and skin. In tumor tissues, it stains carcinomas of the breast, gastrointestinal tract, lung, kidney, urinary bladder and ovary.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.