BTN3A1/2/3 Antibody [Janelia Fluor® 669]

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: Janelia Fluor 669

BTN3A1/2/3 Antibody [Janelia Fluor® 669] Summary

• Immunogen: Chinese hamster ovary cell line CHO-derived recombinant human BTN3A2
  Gln30-Trp248
  Accession # P78410
• Specificity: Detects human BTN3A1, BTN3A2 and BTN3A3 in direct ELISAs and Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Gene: BTN3A2
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for BTN3A1/2/3 Antibody [Janelia Fluor® 669]

• BT3.1
• BTF5
• BTN3.1
• BTN3A1/2/3
• butyrophilin subfamily 3 member A1
• CD277
• dJ45P21.3 (butyrophilin, subfamily 3, member A1)

Background

The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC)-associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene (MIM 601610) and the BTN2 (e.g., BTN2A1; MIM 613590) and BTN3 (e.g., BNT3A1) genes, which have undergone tandem duplication, resulting in 3 copies of each (summary by Smith et al., 2010 [PubMed 20208008]).[supplied by OMIM, Nov 2010]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: BTN3A2