BTN3A1/2/3 Antibody (849203) [Unconjugated]

Images

 
Human peripheral blood lymphocytes were stained with Mouse Anti-Human CD277/BTN3A1 Monoclonal Antibody (Catalog # MAB7136, filled histogram) or isotype control antibody (Catalog # MAB002, open histogram), followed by ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, CyTOF-ready
Clone
849203
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

BTN3A1/2/3 Antibody (849203) [Unconjugated] Summary

Additional Information
Recombinant Monoclonal Antibody.
Immunogen
Chinese hamster ovary cell line CHO-derived recombinant human CD277/BTN3A1
Met1-Gly254
Accession # O00481
Specificity
Detects human BTN3A1, BTN3A2 and BTN3A3 in direct ELISAs.
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
BTN3A1
Purity Statement
Protein A or G purified from cell culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry 0.25 ug/10^6 cells

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for BTN3A1/2/3 Antibody (849203) [Unconjugated]

  • BTN3A1/2/3

Background

Butyrophilin 3A1 (BTN3A1), also known as CD277, has high structural homology to the B7 superfamily of proteins and is expressed in various immune cells such as T and NK cells. BTN3A1 enhances TCR-induced cytokine production and cell proliferation. Early T-cell activation events such as TCR-induced cell signaling are increased upon BTN3A1 engagement. The BTN3A1 co-stimulatory pathway may be involved in the regulation of various cell-mediated immune responses.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs for BTN3A1/2/3 Antibody (MAB7136) (0)

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Secondary Antibodies

 

Isotype Controls

Additional BTN3A1/2/3 Products

Array MAB7136

Bioinformatics Tool for BTN3A1/2/3 Antibody (MAB7136)

Discover related pathways, diseases and genes to BTN3A1/2/3 Antibody (MAB7136). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Omicron Variant Antibodies

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Bioinformatics

Gene Symbol BTN3A1
Uniprot