BRM Antibody

Product Discontinued

BRM Antibody Summary

• Immunogen: SMARCA2 (NP_003061, 659 a.a. ~ 736 a.a) partial recombinant protein with GST tag.KILLDPNSEEVSEKDAKQIIETAKQDVDDEYSMQYSARGSQSYYTVAHAISERVEKQSALLINGTLKHYQLQGLEWM
• Specificity: SMARCA2 - SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
• Clonality: Polyclonal
• Host: Mouse
• Gene: SMARCA2
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot 1:500
• Application Notes: The quality control of this antibody is limited to Western blot on the immunizing protein. It has also been used for ELISA. Abnova's recommended working dilutions for western analysis are as follows: 1:500 dilution for ascites 1:1000 for purified Ig 1:500

Reactivity Notes

Human. Other species not tested.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: Unpurified antisera so the specific antibody concentration is unknown. Contains 50% glycerol.
• Preservative: No Preservative
• Purity: Unpurified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for BRM Antibody

• ATP-dependent helicase SMARCA2
• BAF190B
• BRG1-associated factor 190B
• BRM
• BRMFLJ36757
• EC 3.6.1
• EC 3.6.4.-
• global transcription activator homologous sequence
• hBRM
• hBRMMGC74511
• hSNF2a
• probable global transcription activator SNF2L2
• Protein brahma homolog
• SMARCA2
• SNF2
• SNF2/SWI2-like protein 2
• SNF2A
• SNF2-alpha
• SNF2L2
• SNF2L2BAF190
• SNF2LA
• SNF2-like 2
• Sth1p
• subfamily a, member 2
• sucrose nonfermenting 2-like protein 2
• SWI/SNF related, matrix associated, actin dependent regulator of chromatin
• SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a2
• SWI/SNF-related matrix-associated actin-dependent regulator of chromatinsubfamily A member 2
• SWI2

Background

The protein encoded by this gene is a member of the SWI/SNF family of proteins and is highly similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. Two transcript variants encoding different isoforms have been found for this gene, which contains a trinucleotide repeat (CAG) length polymorphism.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SMARCA2
• Entrez:
  • 6595(Human)
• OMIM:
  • 600014(Human)
• Uniprot:
  • NP_003061(Human)