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Bradykinin RB2/BDKRB2 Antibody (471902) [Alexa Fluor® 405]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
471902
Clonality
Monoclonal
Host
Mouse
Conjugate
Alexa Fluor 405

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB9434U-100UG
Alexa Fluor 488
FAB9434G-100UG
Alexa Fluor 594
FAB9434T-100UG
Alexa Fluor 647
FAB9434R-100UG
Alexa Fluor 700
FAB9434N-100UG
Alexa Fluor 750
FAB9434S-100UG
Unconjugated
MAB9434-100
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB9434-100
Carrier Free
MAB9434-100
Carrier Free
MAB9434-SP
Carrier Free
FAB9434U-100UG
Carrier Free
FAB9434T-100UG
Carrier Free
FAB9434S-100UG
Carrier Free
FAB9434R-100UG
Carrier Free
FAB9434N-100UG
Carrier Free
FAB9434G-100UG
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Bradykinin RB2/BDKRB2 Antibody (471902) [Alexa Fluor® 405] Summary

Immunogen
NS0 mouse myeloma cell line transfected with human RB2/BDKRB2
Met1-Gln391
Accession # P30411
Specificity
Detects human RB2/BDKRB2 in direct ELISAs and Western blots.
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Flow Cytometry 0.25-1 ug/10^6 cells

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Bradykinin RB2/BDKRB2 Antibody (471902) [Alexa Fluor® 405]

  • B2 bradykinin receptor
  • B2R
  • BDKRB2
  • BK-2 receptor
  • BK2
  • BK-2
  • BKR2
  • Bradykinin RB2
  • bradykinin receptor B2
  • BradykininRB2
  • BRB2
  • DKFZp686O088

Background

Bradykinin RB2 (BDKRB2) is a receptor for bradykinin. The 9 aa bradykinin peptide elicits many responses including vasodilation, edema, smooth muscle spasm and pain fiber stimulation. BDKRB2 expression is widespread in normal smooth muscle tissue and neurons. BDKRB2 associates with G proteins that stimulate a phosphatidylinositol-calcium second messenger system. BDKRB2 forms a complex with PECAM1 and GNAQ and interacts with PECAM1. Aging cardiac endothelial cells gradually lose their capacity to express BDKRB2. This loss appears to be parallel with a loss of the angiogenic potential of the aging cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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OXER1/5-oxo-ETE
GPCR Antibody
NLS2272
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Bradykinin
RB2/BDKRB2 Antibody ( ...
FAB9434V
Bradykinin RB2/BDKRB2 Antibody (471902) [Alexa Fluor® 405]
Species: Hu
Applications: Flow

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 FAB9434U
Alexa Fluor 405 FAB9434V
Alexa Fluor 488 FAB9434G
Alexa Fluor 594 FAB9434T
Alexa Fluor 647 FAB9434R
Alexa Fluor 700 FAB9434N
Alexa Fluor 750 FAB9434S
Learn about Custom Antibody Labeling

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Simple Western lane view shows lysates of COLO 205 human colorectal adenocarcinoma cell line and MBA‑MB‑468 human breast cancer cell line, loaded at 0.2 mg/mL. A specific band was detected for EphB2 at approximately 139 and 146 kDa (as indicated) using 20 µg/mL of Goat Anti-Human/Mouse EphB2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF467) followed by 1:50 dilution of HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF109). This experiment was conducted under reducing conditions and using the 12-230 kDa separation system.
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