BMPR-IB/ALK-6 Antibody (3A8)

Western Blot: BMPR-IB/ALK-6 Antibody (3A8) [H00000658-M02] - Analysis of BMPR1B expression in transfected 293T cell line by BMPR1B monoclonal antibody (M02), clone 3A8.Lane 1: BMPR1B transfected lysate(57 KDa).Lane 2: Non-transfected lysate.

ELISA: BMPR-IB/ALK-6 Antibody (3A8) [H00000658-M02] - Detection limit for recombinant GST tagged BMPR1B is approximately 0.3ng/ml as a capture antibody.

Product Discontinued

BMPR-IB/ALK-6 Antibody (3A8) Summary

• Description: Quality control test: Antibody Reactive Against Recombinant Protein.
• Immunogen: BMPR1B (AAH47773, 14 a.a. ~ 103 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. KKEDGESTAPTPRPKVLRCKCHHHCPEDSVNNICSTDGYCFTMIEEDDSGLPVVTSGCLGLEGSDFQCRDTPIPHQRRSIECCTERNECN
• Specificity: BMPR1B - bone morphogenetic protein receptor, type IB
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: BMPR1B
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot 1:500
• Application Notes: Antibody reactivity against transfected lysate and recombinant protein for WB. It has been used for ELISA.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for BMPR-IB/ALK-6 Antibody (3A8)

• activin receptor-like kinase 6
• ALK-6
• ALK6CDw293
• BMP type-1B receptor
• BMPR1B
• BMPR-1B
• BMPRIB
• BMPR-IB
• bone morphogenetic protein receptor type-1B
• bone morphogenetic protein receptor, type IB
• CDw293 antigen
• CDw293
• EC 2.7.11
• EC 2.7.11.30
• serine/threonine receptor kinase

Background

This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: BMPR1B
• Entrez:
  • 658(Human)
• Uniprot:
  • AAH47773(Human)