BMPR-IB/ALK-6 Products

Description

This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension.

Bioinformatics

Entrez	658 Human
Uniprot	NP_001194.1 Human
Product By Gene ID	658
Alternate Names	activin receptor-like kinase 6 ALK-6 ALK6CDw293 BMP type-1B receptor BMPR1B BMPR-1B BMPRIB BMPR-IB bone morphogenetic protein receptor type-1B bone morphogenetic protein receptor, type IB CDw293 antigen CDw293 EC 2.7.11 EC 2.7.11.30 serine/threonine receptor kinase

Research Areas for BMPR-IB/ALK-6

Find related products by research area and learn more about each of the different research areas below.

Mesenchymal Stem Cell Markers
Protein Kinase
Stem Cell Markers