BMPR-IB/ALK-6 Antibody (2F3)

Images

 
Western Blot: BMPR-IB/ALK-6 Antibody (2F3) [H00000658-M01] - Analysis of BMPR1B expression in transfected 293T cell line by BMPR1B monoclonal antibody (M01), clone 2F3.Lane 1: BMPR1B transfected lysate(56.9 KDa).Lane 2: ...read more
Western Blot: BMPR-IB/ALK-6 Antibody (2F3) [H00000658-M01] - Analysis of BMPR1B over-expressed 293 cell line, cotransfected with BMPR1B Validated Chimera RNAi ( Cat # H00000658-R01V ) (Lane 2) or non-transfected control ...read more
Sandwich ELISA: BMPR-IB/ALK-6 Antibody (2F3) [H00000658-M01] - Detection limit for recombinant GST tagged BMPR1B is approximately 0.1ng/ml as a capture antibody.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, RNAi
Clone
2F3
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

BMPR-IB/ALK-6 Antibody (2F3) Summary

Immunogen
BMPR1B (AAH47773, 14 a.a. - 502 a.a.) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. KKEDGESTAPTPRPKVLRCKCHHHCPEDSVNNICSTDGYCFTMIEEDDSGLPVVTSGCLGLEGSDFQCRDTPIPHQRRSIECCTERNECNKDLHPTLPPLKNRDFVDGPIHHRALLISVTVCSLLLVLIILFCYFRYKRQETRPRYSIGLEQDETYIPPGESLRDLIEQSQSSGSGSGLPLLVQRTIAKQIQMVKQIGKGRYGEVWMGKWRGEKVAVKVFFTTEEASWFRETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDYLKSTTLDAKSMLKLAYSSVSGLCHLHTEIFSTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVKFISDTNEVDIPPNTRVGTKRYMPPEVLDESLNRNHFQSYIMADMYSFGLILWEVARRCVSGGIVEEYQLPYHDLVPSDPSYEDMREIVCIKKLRPSFPNRWSSDECLRQMGKLMTECWAHNPASRLTALRVKKTFAKMSESQDIKL
Specificity
BMPR1B - bone morphogenetic protein receptor, type IB
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
BMPR1B
Purity
IgG purified
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Applications/Dilutions

Dilutions
  • Western Blot
  • ELISA
  • RNA Inhibition
Application Notes
Antibody reactivity against recombinant protein for WB. It has been used for RNAi Validation and ELISA.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
IgG purified

Notes

Quality control test: Antibody Reactive Against Recombinant Protein.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for BMPR-IB/ALK-6 Antibody (2F3)

  • activin receptor-like kinase 6
  • ALK-6
  • ALK6CDw293
  • BMP type-1B receptor
  • BMPR1B
  • BMPR-1B
  • BMPRIB
  • BMPR-IB
  • bone morphogenetic protein receptor type-1B
  • bone morphogenetic protein receptor, type IB
  • CDw293 antigen
  • CDw293
  • EC 2.7.11
  • EC 2.7.11.30
  • serine/threonine receptor kinase

Background

This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Diseases for BMPR-IB/ALK-6 Antibody (H00000658-M01)

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Bioinformatics

Gene Symbol BMPR1B
Entrez
OMIM
Uniprot