Mouse BMP-1/PCP ELISA Kit (Colorimetric)

ELISA: Mouse BMP-1/PCP ELISA Kit (Colorimetric) [NBP2-69979] - Samples were spiked with high concentrations of Mouse BMP-1/PCP and diluted with Reference Standard & Sample Diluent to produce samples with values within the range of the assay.

ELISA: Mouse BMP-1/PCP ELISA Kit (Colorimetric) [NBP2-69979] - Standard Curve Reference

• Reactivity: Mu
• Applications: ELISA
• Suitable Sample Type: Serum, plasma and other biological fluids
• Standard Curve Range: 78.13 - 5000 pg/mL
• Sensitivity: 46.88 pg/mL

Mouse BMP-1/PCP ELISA Kit (Colorimetric) Summary

• Specificity: This kit recognizes Mouse BMP-1 in samples. No significant cross-reactivity or interference between Mouse BMP-1 and analogues was observed.
• Standard Curve Range: 78.13 - 5000 pg/mL
• Sensitivity: 46.88 pg/mL
• Assay Type: Sandwich-ELISA
• Inter-Assay: CV% < 5.66%
• Intra-Assay: CV% < 4.33%
• Spike Recovery: 87-107%
• Sample Volume: 100 uL
• Kit Type: ELISA Kit (Colorimetric)
• Gene: BMP1

Applications/Dilutions

• Dilutions:
  • ELISA

Packaging, Storage & Formulations

• Storage: Storage of components varies. See protocol for specific instructions.

Alternate Names for Mouse BMP-1/PCP ELISA Kit (Colorimetric)

• BMP1
• BMP-1
• bone morphogenetic protein 1
• EC 3.4.24
• EC 3.4.24.19
• FLJ44432
• Mammalian tolloid protein
• mTld
• PCOLC
• PCP
• PCP2
• procollagen C-endopeptidase
• Procollagen C-proteinase
• TLD

Background

Bone morphogenetic protein 1 (BMP1) is a 986 amino acid member of the bone morphogenetic protein (BMP) family. It was initially discovered for its role to induce cartilage and bone formation. It is a metalloprotease that cleaves the C-terminus of procollagen I, II and III while other BMPs are part of the TGF beta superfamily. It may play a role in herniation, congestive heart failure, breast cancer, myelofibrosis with myeloid metaplasia and infection by HIV-1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

Publications for BMP-1/PCP ELISA Kit (NBP2-69979)(2)

Publications using NBP2-69979

• Sharma RK, Kamble SH, Krishnan S et al. Involvement of lysyl oxidase in the pathogenesis of arterial stiffness in chronic kidney disease American journal of physiology. Renal physiology 2023-04-01 [PMID: 36825626] (ELISA)
• Vukicevic S, Colliva A, Kufner V et al. Bone morphogenetic protein 1.3 inhibition decreases scar formation and supports cardiomyocyte survival after myocardial infarction Nature communications 2022-01-10 [PMID: 35013172] (ELISA)

Bioinformatics

• Gene Symbol: BMP1