BMP-1/PCP Antibody (264801) [DyLight 550]

• Reactivity: Hu
• Applications: IHC
• Clone: 264801
• Clonality: Monoclonal
• Host: Rat
• Conjugate: DyLight 550

BMP-1/PCP Antibody (264801) [DyLight 550] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human BMP‑1/PCP
  Ala121-Gln730
  Accession # NP_001190
• Specificity: Detects human BMP-1/PCP in direct ELISA.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for BMP-1/PCP Antibody (264801) [DyLight 550]

• BMP1
• BMP-1
• bone morphogenetic protein 1
• EC 3.4.24
• EC 3.4.24.19
• FLJ44432
• Mammalian tolloid protein
• mTld
• PCOLC
• PCP
• PCP2
• procollagen C-endopeptidase
• Procollagen C-proteinase
• TLD

Background

Bone morphogenetic protein 1 (BMP1) is a 986 amino acid member of the bone morphogenetic protein (BMP) family. It was initially discovered for its role to induce cartilage and bone formation. It is a metalloprotease that cleaves the C-terminus of procollagen I, II and III while other BMPs are part of the TGF beta superfamily. It may play a role in herniation, congestive heart failure, breast cancer, myelofibrosis with myeloid metaplasia and infection by HIV-1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.