Blk Antibody - BSA Free

Immunohistochemistry-Paraffin: Blk Antibody [NBP3-41291] - DAB staining on IHC-P; Samples: Human Breast cancer Tissue; Primary Ab: 30ug/ml NBP3-41291; Second Ab: 2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody

Immunohistochemistry-Paraffin: Blk Antibody [NBP3-41291] - DAB staining on IHC-P; Samples: Human Lymph node Tissue; Primary Ab: 20ug/ml NBP3-41291; Second Ab: 2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody

Western Blot: Blk Antibody [NBP3-41291] - Sample: Porcine Cerebrum lysate; Primary Ab: 1ug/ml NBP3-41291; Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody

• Reactivity: Hu, Mu, Rt, Po
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 0.5 mg/ml

Blk Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit Blk Antibody - BSA Free (NBP3-41291) is a polyclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Immunized with recombinant Human Blk (Uniprot#: P51451; Leu241-Tyr494 (Uniprot#: P51451)
• Clonality: Polyclonal
• Host: Rabbit
• Gene: BLK
• Purity: Antigen and protein A Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 5-20ug/mL
  • Immunohistochemistry-Paraffin 5-20ug/mL
  • Western Blot 0.01-2ug/mL

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 0.01M PBS, pH7.4, 50% glycerol
• Preservative: 0.05% Proclin 300
• Concentration: 0.5 mg/ml
• Purity: Antigen and protein A Affinity-purified

Alternate Names for Blk Antibody - BSA Free

• B lymphocyte kinase
• B lymphoid tyrosine kinase
• BLK nonreceptor tyrosine kinase
• Blk
• EC 2.7.10.2
• MGC10442
• MODY11
• p55-Blk
• tyrosine-protein kinase Blk

Background

BLK ( B lymphoid tyrosine kinase), with 505-amino acid protein (about 56KDa), belongs to the Src non-receptor tyrosine kinases family.Different subcellular localizations of Src-family kinases may be important for the regulation of specific cellular processes such as mitogenesis, cytoskeletal organization, and membrane trafficking.Blk is expressed exclusively by B lymphocytes and it is thought to function in a signal transductory pathway specific to this lineage. B lymphoid expression of an active Blk mutant caused proliferation of B progenitor cells and enhanced responsiveness of these cells to interleukin 7. Thus, sustained activation of Blk induces responses normally associated with the pre-BCR.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: BLK