Hu, Mu, RtApplications:
WB, ELISA, Flow, S-ELISAHost:
Species: Hu, Mu, Rt
Host: Goat Polyclonal
Applications: WB, ELISA, IHC, IHC-P
Host: Mouse Monoclonal
BLK ( B lymphoid tyrosine kinase), with 505-amino acid protein (about 56KDa), belongs to the Src non-receptor tyrosine kinases family.Different subcellular localizations of Src-family kinases may be important for the regulation of specific cellular processes such as mitogenesis, cytoskeletal organization, and membrane trafficking.Blk is expressed exclusively by B lymphocytes and it is thought to function in a signal transductory pathway specific to this lineage. B lymphoid expression of an active Blk mutant caused proliferation of B progenitor cells and enhanced responsiveness of these cells to interleukin 7. Thus, sustained activation of Blk induces responses normally associated with the pre-BCR.
Research Areas for Blk
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Bioinformatics Tool for Blk
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