WB: Approx. 37 kDa band observed in rat skin lysates (calculated MW of 41.7 kDa band according to human NP_001702.1 and rat NP_058783.1). IHC successful usage on human achilles tendons is reported in scientific literature (PMID: 23001016). The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Read Publications using NB100-55407 in the following applications:
Predicted cross-reactivity based on sequence identity: Mouse, Canine.
Alternate Names for Biglycan Antibody
Bone/cartilage proteoglycan I
dermatan sulphate proteoglycan I
small leucine-rich protein 1A
The protein encoded by this gene is a small cellular or pericellular matrix proteoglycan that is closely related in structure to two other small proteoglycans, decorin and fibromodulin. The encoded protein and decorin are thought to be the result of a gene duplication. Decorin contains one attached glycosaminoglycan chain, while this protein probably contains two chains. For this reason, this protein is called biglycan. This protein is thought to function in connective tissue metabolism by binding to collagen fibrils and transfering growth factor-beta. It may promote neuronal survival. This gene is a candidate gene for the Happle syndrome.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.