Mouse beta-Defensin 3 Protein Summary
A biologically active protein to DEFB103B.
Source: E. coli
Amino Acid Sequence: KKINNPVSCL RKGGRCWNRC IGNTRQIGSC GVPFLKCCKR K
Novus' biologically active proteins are stringently purified to provide only the safest and most highly effective proteins available. This protein was expressed in E. coli, purified by HPLC, QC tested by SDS-PAGE and Western Blot and validated on appropriate cell lines for bioactivity. All HPLC and bioactivity data is provided for your assurance.
|Details of Functionality
Defensin beta 3 Protein is fully biologically active when compared to standard. The ED50 as determined by anti-microbial activity against E.coli. is less than 20 ug/ml, corresponding to a specific activity of > 50 IU/mg.
>95% pure by SDS-PAGE
Less than 1EU/ug of endotoxin as determined by LAL method.
Packaging, Storage & Formulations
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
>95% pure by SDS-PAGE
Reconstitute with sterilized distilled water or 0.1% BSA aqueous buffer to a final concentration of 0.1 - 1.0 mg/ml.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
This lyophilized preparation is stable at 2-8 degrees C, but should be kept at -20 degrees C for long term storage, preferably desiccated. Upon reconstitution, the preparation is most stable at -20 to -80 degrees C, and can be stored for one week at 2-8 degrees C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 degrees C to -80 degrees C. Avoid repeated freeze/thaw cycles.
Alternate Names for Mouse beta-Defensin 3 Protein
- beta-defensin 103
- betaDefensin 3
- Beta-defensin 3
- Defensin, beta 103
- defensin, beta 103B
- Defensin-like protein
Defensins (alpha and beta) are cationic peptides with antimicrobial activity against Gram-negative and Gram-positive bacteria, fungi, and enveloped viruses. They are 2-6 k Da proteins and take important roles in innate immune system. On the basis of their size and pattern of disulfide bonding, mammalian defensins are classified into alpha, beta and theta categories. beta-Defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. Four human beta-defensins have been identified and they are expressed on some leukocytes and at epithelial surfaces. Because beta-defensins is cationic peptides, they can therefore interact with the membrane of invading microbes, which are negative due to lipopolysaccharides (LPS) and lipoteichoic acid (LTA) found in the cell membrane. Especially, they have higher affinity to the binding site compared to Ca 2+ and Mg2+ ions. Furthermore, they can affect the stability of the membrane.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed
for 2 years from date of receipt.
Customers Who Viewed This Item Also Viewed...
Applications: WB, IHC
Applications: Func, PAGE
Applications: WB, Flow, ICC/IF, IHC, IHC-P, IP
Species: Hu, Ca
Applications: B/N, Flow, ICC/IF, IP, In vitro, Flow-CS, Flow-IC
Applications: Flow, ICC
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Species: Hu, Mu, Pm
Applications: WB, ICC/IF, IHC, IHC-P
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P, IP
Species: Hu, Rt, Ca, Mk
Applications: WB, IHC, IHC-P, IP
Species: Hu, Mu
Applications: WB, Simple Western, ChIP, IP
Publications for beta-Defensin 3 Protein (NBP2-35146) (0)
There are no publications for beta-Defensin 3 Protein (NBP2-35146).
By submitting your publication information earn gift cards and discounts for future purchases.
Reviews for beta-Defensin 3 Protein (NBP2-35146) (0)
There are no reviews for beta-Defensin 3 Protein (NBP2-35146).
By submitting a review earn points towards our Rewards Program.
- 250 points for product review
- 500 additional points for an image with your product review
- Double points (500) if you are the first to review this product
- Double points (1000) if you are the first to review this product with an image
FAQs for beta-Defensin 3 Protein (NBP2-35146) (0)
Additional Mouse beta-Defensin 3 Protein Products
Related Products by Gene
, BETA-DEFENSIN 2
, MELANOCORTIN 1 RECEPTOR
Bioinformatics Tool for beta-Defensin 3 Protein (NBP2-35146)
Discover related pathways, diseases and genes to beta-Defensin 3 Protein (NBP2-35146). Need help?
Read the Bioinformatics Tool Guide
for instructions on using this tool.
Blogs on beta-Defensin 3.