Human beta 2-Microglobulin ELISA Kit

Product Discontinued

Human beta 2-Microglobulin ELISA Kit Summary

• Standard Curve Range: 0.19 to 200 ng/mL
• Sensitivity: 0.19 ng/mL
• Inter-Assay: CV% < 7.20%
• Intra-Assay: CV% < 4.90%
• Spike Recovery: 97.50%
• Sample Volume: 50 uL
• Kit Type: ELISA Kit
• Gene: B2M

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: B2M (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human B2M in plasma, serum, urine, and cell culture supernatants.

Reactivity Notes

Human

Packaging, Storage & Formulations

• Storage: Storage of components varies. See protocol for specific instructions.

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Human beta 2-Microglobulin ELISA Kit

• B2M
• beta 2Microglobulin
• beta 2-Microglobulin
• beta chain of MHC class I molecules
• beta-2-microglobin
• beta-2-microglobulin

Background

Beta-2-microglobulin is a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells (Gussow et al., 1987 [PubMed 3312414]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

Publications for beta 2-Microglobulin ELISA Kit (KA1045)(3)

Publications using KA1045

• Eakin CM, Berman AJ, Miranker AD. A native to amyloidogenic transition regulated by a backbone trigger. Nat Struct Mol Biol. 2006-03-01 [PMID: 16491088]
• Corlin DB, Sen JW, Ladefoged S et al. Quantification of cleaved beta2-microglobulin in serum from patients undergoing chronic hemodialysis. Clin Chem. 2005-07-01 [PMID: 15890888]
• Trinh CH, Smith DP, Kalverda AP et al. Crystal structure of monomeric human beta-2-microglobulin reveals clues to its amyloidogenic properties. Proc Natl Acad Sci U S A. 2002-07-23 [PMID: 12119416]

FAQs for beta 2-Microglobulin ELISA Kit (KA1045). (Showing 1 - 1 of 1 FAQs).

1. What is the difference between the Quantikine and Duoset ELISA kits?
   • Our Quantikine kits are fully optimized and validated for the sample types listed on the product specific webpage and datasheet, as this can vary between kits. Each kit is supplied ready to use with one pre-coated 96-well plate, a detection antibody directly conjugated to HRP, and all other necessary reagents. These kits are ideal for researchers who want the convenience of a ready to use and optimized ELISA product. Some of these kits are also available prepackaged in larger 6 and 50 plate sizes.Our DuoSet Kits, in contrast, are ELISA development kits containing the capture and detection antibody, the mass-value calibrated standard, and streptavidin-HRP to prepare approximately 5 or 15 plates. Ancillary reagents will need to be used/purchased, and for most kits, we will recommend one of our Ancillary Reagent Kits, which contain the reagents we use ourselves in-house. DuoSet kits are validated only for cell culture supernatant samples and therefore require further development and validation for accurate measurement in more complex samples such as serum and plasma. Our DuoSet Kits offer an economical, flexible alternative for the experienced ELISA user.

Bioinformatics

• Gene Symbol: B2M