beta 2-Microglobulin Antibody (2M2) [FITC]

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Flow Cytometry: beta 2-Microglobulin Antibody (2M2) [FITC] [NB100-77981] - Human peripheral blood lymphocytes stained with 2M2 FITC

Product Details

Summary
Product Discontinued
View other related beta 2-Microglobulin Primary Antibodies

Order Details


    • Catalog Number
      NB100-77981
    • Availability
      Product Discontinued

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beta 2-Microglobulin Antibody (2M2) [FITC] Summary

Immunogen
Purified human beta2-microglobulin
Specificity
beta 2 Microglobulin(2M2)
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
B2M
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry 1:10-1:1000
Application Notes
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is: 1.0 microgram per million cells or 100 microliter of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Positive Control
beta 2-Microglobulin Lysate (NBL1-07874)

Reactivity Notes

Expected Cross-Reactivity based on immunogen sequence: Swine (Pig, Porcine).

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS (pH 7.2) and 0.2% (w/v) BSA
Preservative
0.09% Sodium Azide
Concentration
0.5 mg/ml
Purity
Protein A or G purified

Alternate Names for beta 2-Microglobulin Antibody (2M2) [FITC]

  • B2M
  • beta 2Microglobulin
  • beta 2-Microglobulin
  • beta chain of MHC class I molecules
  • beta-2-microglobin
  • beta-2-microglobulin

Background

beta 2 Microglobulin is a 12 kD nonpolymorphic Ig like protein. It is a non-membrane-anchored glycoprotein and is noncovalently associated with 39-44 kD polymorphic heavy chains of MHC class I molecules to form HLA class I antigen complex. In association with HLA class I, beta 2 Microglobulin is expressed on all leukocytes, platelets, endothelial cells, and epithelial cells. beta 2 Microglobulin plays an essential role both in governing MHC class I molecules stability and in promoting antigen binding and presenting the antigen to CD3/TCR complex of CD8+ T cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for beta 2-Microglobulin Antibody (NB100-77981)

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Bioinformatics

Gene Symbol B2M
Entrez