Bestrophin 2 Antibody

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Immunohistochemistry-Paraffin: Bestrophin 2 Antibody [NB110-55620] - Analysis of anti-BEST2 / Bestrophin-2 antibody with human testis.

Product Details

Summary
Reactivity Hu, Mu, Rt, Po, Bv, Ha, Pm, Bt, Ca, Ma-Op, Pm, RbSpecies Glossary
Applications IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

Bestrophin 2 Antibody Summary

Immunogen
Synthetic 17 amino acid peptide from internal region of human Bestrophin 2.
Specificity
Human Bestrophin 2. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except BEST3 (59%).
Predicted Species
Canine (94%), Bat (94%), Primate (100%), Rabbit (94%), Opossum (94%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
BEST2
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 2.5 - 5 ug/ml
Control
Bestrophin 2 Overexpression Lysate

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (88%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Bestrophin 2 Antibody

  • bestrophin 2
  • FLJ20132
  • vitelliform macular dystrophy 2-like 1
  • Vitelliform macular dystrophy 2-like protein 1
  • VMD2L1bestrophin-2
  • VMD2-like gene 1

Background

This gene is a member of the bestrophin gene family of anion channels. Bestrophin genes share a similar gene structure with highly conserved exon-intron boundaries, but with distinct 3' ends. Bestrophins are transmembrane proteins that contain a homologous region rich in aromatic residues, including an invariant arg-phe-pro motif. Mutation in one of the family members (bestrophin 1) is associated with vitelliform macular dystrophy. The bestrophin 2 gene is mainly expressed in the retinal pigment epithelium and colon.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for Bestrophin 2 Antibody (NB110-55620)

Discover related pathways, diseases and genes to Bestrophin 2 Antibody (NB110-55620). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Pathways for Bestrophin 2 Antibody (NB110-55620)

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Blogs on Bestrophin 2.

"I can see clearly now": Targeting Bestrophin 1 to treat Bestrophinopathies
Encoded by the VMD2 gene on chromosome 11q13 Bestrophin 1 is the prototypic member of the RFP family of proteins which are more commonly called "bestrophins". The protein family was originally identified in Caenorhabditis elegans based on a conserved...  Read full blog post.

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Bioinformatics

Gene Symbol BEST2
Entrez
Uniprot