Bestrophin 2 Products

Description

Bestrophin 2 is a member of the bestrophin gene family of anion channels. Bestrophin genes share a similar gene structure with highly conserved exon-intron boundaries, but with distinct 3' ends. Bestrophins are transmembrane proteins that contain a homologous region rich in aromatic residues, including an invariant arg-phe-pro motif. Mutation in one of the family members (bestrophin 1) is associated with vitelliform macular dystrophy. The bestrophin 2 gene is mainly expressed in the retinal pigment epithelium and colon.

Bioinformatics

Entrez	54831 Human
Uniprot	Q8NFU1 Human NM_017682 Human
Product By Gene ID	54831
Alternate Names	vitelliform macular dystrophy 2-like 1 VMD2-like gene 1 FLJ20132 VMD2L1bestrophin-2 Vitelliform macular dystrophy 2-like protein 1 bestrophin 2

Diseases related to Bestrophin 2

Discover more about diseases related to Bestrophin 2.

Intraocular Pressure Disorder
Vitelliform Macular Dystrophy
Age Related Macular Degeneration
Aqueous Humor Disorders
Glaucoma
Cystic Fibrosis
Fibrosis
Dystrophy
Disorder Of Eye
Microphthalmos
Retinal Degeneration
Edema
Scleral Diseases
Dysentery
Encephalitis
Diarrhea
Retinal Diseases
Anhidrosis
Fibrocystic Disease Of Pancreas
Salivary Gland Diseases

Pathways for Bestrophin 2

View related products by pathway and learn more about each of the pathways below.

Secretion
Transport
Ion Transport
Localization
Bicarbonate Transport
Gland Morphogenesis
Saliva Secretion
Phagocytosis
Anion Homeostasis
Anion Transport

Bioinformatics Tool for Bestrophin 2

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Related Bestrophin 2 Blog Posts

Check out the latest blog posts on Bestrophin 2.

"I can see clearly now": Targeting Bestrophin 1 to treat Bestrophinopathies Encoded by the VMD2 gene on chromosome 11q13 Bestrophin 1 is the prototypic member of the RFP family of proteins which are more commonly called "bestrophins". The protein family was originally identified in Caenorhabditis elegans based on a conserved...    Read more.

Read more Bestrophin 2 related blogs.