BCCIP Antibody

Western Blot: BCCIP Antibody [NBP1-22993] - Whole cell lysate from HeLa and 293T cells. BCCIP was also immunoprecipitated by rabbit anti-BCCIP antibody NBP1-22994.

• Reactivity: Hu
• Applications: WB, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Concentration: 0.2 mg/ml

BCCIP Antibody Summary

• Immunogen: The immunogen recognized by this antibody maps to a region between residue 1 and 50 of human BRCA2 and CDKN1A interacting protein using the numbering given in entry NP_510868.1 (GeneID 56647).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: BCCIP
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation 2-5 ug/mg lysate
  • Western Blot 1:2000-1:10000

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: TBS and 0.1% BSA
• Preservative: 0.09% Sodium Azide
• Concentration: 0.2 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for BCCIP Antibody

• BCCIPalpha
• BRCA2 and CDKN1A interacting protein
• BRCA2 and CDKN1A-interacting protein
• BRCA2 and Cip1/p21 interacting protein
• cdk inhibitor p21 binding protein
• P21- and CDK-associated protein 1
• Protein TOK-1
• TOK-1
• TOK-1alpha
• TOK1BCCIPbeta
• TOK-1beta

Background

BCCIP (BRCA2 and CDKN1A interacting protein) was isolated as a BRCA2 and p21 interacting protein. Downregulation of BCCIP results in chromosome instability and incomplete cytokinesis indicating a role in DNA damage. Additionally, BCCIP is critical for BRCA2- and Rad51-dependent homologous recombinational repair.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: BCCIP
• Entrez:
  • 56647(Human)
• Uniprot:
  • Q9P287(Human)