BATF3 Antibody (841702) [Alexa Fluor™ Plus 488]

• Reactivity: Hu
• Clone: 841702
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 488

BATF3 Antibody (841702) [Alexa Fluor™ Plus 488] Summary

• Specificity: Detects human BATF3 in ELISA.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for BATF3 Antibody (841702) [Alexa Fluor™ Plus 488]

• basic leucine zipper transcription factor, ATF-like 3
• basic leucine zipper transcriptional factor ATF-like 3
• BATF3
• B-ATF-3
• FLJ36352
• FLJ37535,21 kDa small nuclear factor isolated from T-cells
• JDP1
• Jun dimerization protein 1
• Jun dimerization protein p21SNFT
• JUNDM1
• SNFT
• SNFT21-kD small nuclear factor isolated from T cells

Background

BATF3 (Basic leucine zipper transcriptional factor ATF-like 3; also p21SNFT) is a 20 kDa nuclear member of the bZIP family of proteins. It is expressed in Th1 cells and conventional dendritic cells (CD11c⁺), and serves to downregulate AP-1 mediated transcription. BATF3 accomplishes this by heterodimerizing with Jun and binding to AP-1 consensus binding sites, thus precluding a Jun/Fos interaction with gene activation. Human BAFT3 is 127 amino acids (aa) in length. It contains one DNA binding motif (aa 41-59) with an adjacent leucine-zipper (aa 63-84), but lacks a transactivation domain. Full-length human BATF3 (aa 1-127) shares 80% aa sequence identity with mouse BATF3.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.