B4GALT7 Antibody

Images

 
Western Blot: B4GALT7 Antibody [H00011285-B01P] - Analysis of B4GALT7 expression in HepG2.
Western Blot: B4GALT7 Antibody [H00011285-B01P] - Analysis of B4GALT7 expression in transfected 293T cell line by B4GALT7 polyclonal antibody. Lane 1: B4GALT7 transfected lysate(35.97 KDa). Lane 2: Non-transfected ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clonality
Polyclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

B4GALT7 Antibody Summary

Immunogen
B4GALT7 (NP_009186.1, 1 a.a. ~ 327 a.a) full-length human protein.MFPSRRKAAQLPWEDGRSGLLSGGLPRKCSVFHLFVACLSLGFFSLLWLQLSCSGDVARAVRGQGQETSGPPRACPPEPPPEHWEEDASWGPHRLAVLVPFRERFEELLVFVPHMRRFLSRKKIRHHIYVLNQVDHFRFNRAALINVGFLESSNSTDYIAMHDVDLLPLNEELDYGFPEAGPFHVASPELHPLYHYKTYVGGILLLSKQHYRLCNGMSNRFWGWGREDDEFYRRIKGAGLQLFRPSGITTGYKTF
Specificity
B4GALT7 - xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I),
Isotype
IgG
Clonality
Polyclonal
Host
Mouse
Gene
B4GALT7
Purity
IgG purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500
  • ELISA
Application Notes
Antibody reactive against Recombinant Protein with GST tag on ELISA and Western Blot and also on transfected lysate in western blot. GST tag alone is used as a negative control.

Reactivity Notes

Human.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for B4GALT7 Antibody

  • b4Gal-T7
  • beta-1,4-galactosyltransferase 7
  • Beta-1,4-GalTase 7
  • beta4Gal-T7
  • beta4GalT-VII
  • EC 2.4.1.-
  • proteoglycan UDP-galactose:beta-xylose beta1,4-galactosyltransferase I
  • UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 7
  • UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 7
  • XGALT-1
  • XGALT1beta-1,4-galactosyltransferase VII
  • XGPT1
  • xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7(galactosyltransferase I)

Background

This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene attaches the first galactose in the common carbohydrate-protein (GlcA-beta1,3-Gal-beta1,3-Gal-beta1,4-Xyl-beta1-O-Ser) linkage found in proteoglycans. Manganese is required as a cofactor. This enzyme differs from the other six beta4GalTs because it lacks the conserved beta4GalT1-beta4GalT6 Cys residues and it is located in cis-Golgi instead of trans-Golgi. Two single-nucleotide mutations were identified from a patient with the progeroid type of Ehlers-Danlos syndrome. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol B4GALT7
Entrez
Uniprot