ASPP1 Antibody [mFluor Violet 500 SE]

• Reactivity: Hu
• Applications: IP, WB (-)
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: mFluor Violet 500 SE

ASPP1 Antibody [mFluor Violet 500 SE] Summary

• Immunogen: The immunogen recognized by this antibody maps to a region between residue 50 and 100 of human Apoptosis-Stimulated Protein of p53, 1 using the numbering given in entry NP_056131.1 (GeneID 23368).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PPP1R13B
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for ASPP1 Antibody [mFluor Violet 500 SE]

• apoptosis-stimulating protein of p53, 1
• ASPP1Protein phosphatase 1 regulatory subunit 13B
• KIAA0771apoptosis-stimulating of p53 protein 1
• p53BP2-like
• p85
• protein phosphatase 1, regulatory (inhibitor) subunit 13B

Background

The ASPP family members ASPP1, ASPP2, act as potent activators of p53. A third member of the family, iASPP, has an inhibitory effect on apoptosis. The three members of ASPP family all bind p53 via their C-terminus, which contains a proline-rich region, four ankyrin repeats and an SH3 domain. Expression of ASPP1 and ASPP2 is frequently downregulated in human breast tumors expressing wild-type p53. ASPP1 may also play a role in vascular development.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PPP1R13B