HEK293 human embryonic kidney cell line transfected with (A) human ASGR2 or (B) irrelevant transfectants and eGFP was stained with Mouse Anti-Human ASGR2 Monoclonal Antibody (Catalog # MAB9970) followed by ...read more
ASGR2 was detected in immersion fixed paraffin-embedded sections of human liver using Rabbit Anti-Human ASGR2 Monoclonal Antibody (Catalog # MAB9970) at 1 µg/mL for 1 hour at room temperature followed by ...read more
Western blot shows lysates of human liver tissue. PVDF membrane was probed with 2 µg/mL of Rabbit Anti-Human ASGR2 Monoclonal Antibody (Catalog # MAB9970) followed by HRP-conjugated Anti-Rabbit IgG Secondary ...read more
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 °C, as supplied.
1 month, 2 to 8 °C under sterile conditions after opening.
6 months, -20 to -70 °C under sterile conditions after opening.
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
Reconstitute at 0.5 mg/mL in sterile PBS.
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Asialoglycoprotein Receptor 2 Antibody (2327C) [Unconjugated]
asialoglycoprotein receptor 2
C-type lectin domain family 4 member H2
Hepatic lectin H2
Asialoglycoprotein receptor 2 (ASGR2) is a subunit of the
Asialoglycoprotein receptor. The asialoglycoprotein receptor is a
hetero-oligomeric protein composed of major and minor subunits, which are
encoded by different genes. The protein encoded by this gene is the less
abundant minor subunit. The asialoglycoprotein receptor may facilitate hepatic
infection by multiple viruses including hepatitis B, and is also a target for
liver-specific drug delivery. Expressed on hepatocytes, the Asialoglycoprotein
receptor mediates endocytosis and lysosomal degradation of glycoproteins to
mediate serum glycoprotein homeostasis. The ASGR receptor binds plasma
glycoproteins which have had the terminal sialic acid residue removed. An
alternatively spliced variant, H2, which can be shed, has been proposed as a
marker for liver fibrosis.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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PRODUCT AVAILABILITY: Update Regarding the Evolving COVID-19 Situation
Bio-Techne appreciates the critical role that you and our products and services play in research efforts to further scientific innovation and discovery. We are continually assessing our manufacturing and supplier capabilities during the COVID-19 situation and are implementing precautionary measures to ensure uninterrupted supply of products and services. Currently, and as we abide by local shelter in place orders across the world, we are fully operational and do not anticipate any material supply disruptions across our Bio-Techne brands and product lines. As the situation evolves, our goal is to utilize preventive measures to reduce the threat that COVID-19 poses to our ability to meet the needs of our customers globally.