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HAF008). A specific band was detected for ASGR2 at approximately 45 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank">
VC003). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to cytoplasm in hepatocytes. View our protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents." class="big_lightbox" target="_blank">
Asialoglycoprotein Receptor 2 is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of plasma glycoproteins in which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. It is expressed exclusively in hepatic parenchymal cells and calcium is required for ligand binding. Asialoglycoprotein Receptor 2 may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. Asialoglycoprotein Receptor 2 is involved in hepatitis B, hepatitis C, liver cirrhosis, hepatocellular carcinoma, nephropathy, leukemia, urethritis, autoimmune hepatitis, alcoholic liver cirrhosis, and jaundice.
![Western Blot Asialoglycoprotein Receptor 2 Antibody (2327C) [Unconjugated]](http://images.novusbio.com/images/antibody/ASGR2_MAB9970_Western_Blot_22519.jpg)
![Bioactivity Asialoglycoprotein Receptor 2 [Unconjugated]](http://images.novusbio.com/images/protein/10447-as_recombinant-mouse-asgr2-fc-chimera-protein-cf-bioactivity-115202012145.jpg)
![Binding Activity Asialoglycoprotein Receptor 2 [Unconjugated]](http://images.novusbio.com/fullsize/protein/ASGR2_9370AS_2080.jpg)
![Flow Cytometry Asialoglycoprotein Receptor 2 Antibody (2327C) [Unconjugated]](http://images.novusbio.com/images/antibody/ASGR2_MAB9970_Flow_Cytometry_22447.jpg)
![Immunohistochemistry Asialoglycoprotein Receptor 2 Antibody (2327C) [Unconjugated]](http://images.novusbio.com/images/antibody/ASGR2_MAB9970_Immunohistochemistry_22512.jpg)
![SDS-Page Asialoglycoprotein Receptor 2 [Unconjugated]](http://images.novusbio.com/fullsize/protein/ASGR2_10447AS_3155.jpg)
