Asialoglycoprotein Receptor 2 Products

Description

Asialoglycoprotein Receptor 2 is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of plasma glycoproteins in which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. It is expressed exclusively in hepatic parenchymal cells and calcium is required for ligand binding. Asialoglycoprotein Receptor 2 may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. Asialoglycoprotein Receptor 2 is involved in hepatitis B, hepatitis C, liver cirrhosis, hepatocellular carcinoma, nephropathy, leukemia, urethritis, autoimmune hepatitis, alcoholic liver cirrhosis, and jaundice.

Bioinformatics

Entrez	433 Human
Uniprot	AAH17251 Human NM_080913 Human NM_080914 Human NP_001172 Human NP_550434 Human NP_550435.1 Human P07307 Human
Product By Gene ID	433
Alternate Names	ASGPR 2 ASGP-R 2 ASGPR2 ASGP-R2 asialoglycoprotein receptor 2 CLEC4H2FLJ60040 C-type lectin domain family 4 member H2 HBxAg-binding protein HBXBP Hepatic lectin H2 HL-2