ARMS2 Antibody

Immunohistochemistry-Paraffin: ARMS2 Antibody [NBP1-52157] - (4ug/ml) staining of paraffin embedded Human Retina. Microwaved antigen retrieval with citrate buffer pH 6, HRP-staining.

Immunohistochemistry-Paraffin: ARMS2 Antibody [NBP1-52157] - (4ug/ml) staining of paraffin embedded Human Retina. Microwaved antigen retrieval with citrate buffer pH 6, HRP-staining.

• Reactivity: Hu
• Applications: ELISA, IHC
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

ARMS2 Antibody Summary

• Immunogen: Peptide with sequence C-EGASDKQRSK corresponding to internal region according to NP_001093137.1.
• Epitope: C-EGASDKQRSK
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: ARMS2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 2-4 ug/ml
  • Peptide ELISA Detection limit 1:4000
• Application Notes: Western blot: Not yet tested - our routinely used western blotting protocol does not allow detection of proteins as small as the calculated size of 11.4kDa according to NP_001093137.1. Therefore we cannot recommend an optimal concentration and the antibody is an aspiring product.
  IHC: In paraffin embedded Human Retina shows cytoplasm staining throughout.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for ARMS2 Antibody

• age-related maculopathy susceptibility 2
• age-related maculopathy susceptibility protein 2
• ARMD8
• LOC387715

Background

The ARMS2 gene encodes a protein that is thought to play a role in diseases in the elderly. Mutations in this gene have beenassociated with age-related macular degeneration. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for ARMS2 Antibody (NBP1-52157)(1)

Publication using NBP1-52157

• Kanda A, Stambolian D, Chen W et al. Age-related macular degeneration-associated variants at chromosome 10q26 do not significantly alter ARMS2 and HTRA1 transcript levels in the human retina. Mol Vis 2010-07-15 [PMID: 20664794]

Bioinformatics

• Gene Symbol: ARMS2
• Entrez:
  • 387715(Human)
• Uniprot:
  • NP_001093137.1(Human)