APC Antibody (SC61-03)

Western Blot: APC Antibody (SC61-03) [NBP2-67625] - Analysis of APC on mouse brain lysates using anti-APC antibody at 1/1,000 dilution.

Immunocytochemistry/Immunofluorescence: APC Antibody (SC61-03) [NBP2-67625] - Staining APC in A431 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Immunocytochemistry/Immunofluorescence: APC Antibody (SC61-03) [NBP2-67625] - Staining APC in 293 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Product Discontinued

APC Antibody (SC61-03) Summary

• Additional Information: Recombinant Monoclonal Antibody.
• Immunogen: Synthetic peptide within Human APC aa 51-100 / 2,843. (SwissProt: P25054 Human; SwissProt: Q61315 Mouse)
• Localization: Cytoplasm, Cell junction, Cell membrane.
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: APC
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:50-1:200
  • Immunoprecipitation
  • Western Blot 1:1000-1:5000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: TBS (pH7.4), 0.05% BSA, 40% Glycerol
• Preservative: 0.05% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein A purified

Alternate Names for APC Antibody (SC61-03)

• adenomatosis polyposis coli tumor suppressor
• adenomatosis polyposis coli
• adenomatous polyposis coli protein
• adenomatous polyposis coli
• APC
• BTPS2
• Deleted in polyposis 2.5
• DP2
• DP2.5DP2
• DP3
• FPC
• GS
• Min
• Protein APC

Background

Adenomatous polyposis coli (APC) is a protein that plays a critical role in several cellular processes. APC is a tumor suppressor, regulates cell division, helps ensure that the number of chromosomes in a cell is correct following cell division and associates with other proteins involved in cell attachment and signaling (1). APC regulates

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: APC