Aminopeptidase PILS/ARTS1 Antibody [Biotin]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Goat
Conjugate
Biotin
Concentration
LYOPH

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Aminopeptidase PILS/ARTS1 Antibody [Biotin] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse Aminopeptidase PILS/ARTS1
Ser27-Leu930
Accession # NP_109636
Specificity
Detects mouse Aminopeptidase PILS/ARTS1 in Western blots. In Western blots, approximately 40% cross-reactivity with recombinant human ARTS1 is observed.
Source
N/A
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
ERAP1
Purity Statement
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Aminopeptidase PILS/ARTS1 Antibody [Biotin]

  • Adipocyte-derived leucine aminopeptidase
  • A-LAP
  • A-LAPALAP
  • Aminopeptidase PILS
  • ARTS1
  • ARTS1aminopeptidase regulator of TNFR1 shedding
  • ARTS-1PILSAP
  • EC 3.4.11
  • EC 3.4.11.-
  • EC 3.4.11.1
  • endoplasmic reticulum aminopeptidase 1
  • endoplasmic reticulum aminopeptidase associated with antigen processing
  • ERAAP1
  • ERAP1
  • KIAA0525APPILS
  • PILS-AP
  • PILS-APERAAP
  • Puromycin-insensitive leucyl-specific aminopeptidase
  • Type 1 tumor necrosis factor receptor shedding aminopeptidase regulator

Background

The mouse ARTS1 gene encodes aminopeptidase PILS (Puromycin-Insensitive Leucyl-Specific), which is also known as adipocyte-derived leucine aminopeptidase, type 1 tumor necrosis factor receptor shedding aminopeptidase regulator and ERAAP (the aminopeptidase associated with antigen processing in the endoplasmic reticulum) (1‑3). The deduced amino acid sequence of mouse ARTS1 consists of a signal peptide and a large ectodomain. Widely expressed and releasing an N‑terminal amino acid (Leu), the enzyme may play a role in many processes such as antigen processing and angiogenesis.

  1. Miyashita, H. et al. (2002) Blood 99:3241.
  2. Serwold, T. et al. (2002) Nature 419:480.
  3. Schomburg, L. (2004) in Handbook of Proteolytic Enzymes. Barrett, et al. eds. p. 311, Academic Press, San Diego.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Biotin BAF2500

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Bioinformatics

Gene Symbol ERAP1
Uniprot