Aminopeptidase A/ENPEP Antibody

ELISA: Aminopeptidase A/ENPEP Antibody [43180002]

Product Discontinued

Aminopeptidase A/ENPEP Antibody Summary

• Immunogen: This antibody is specific for the N Terminus Region of the target protein.
• Specificity: This product is specific for Human ENPEP.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ENPEP
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Western Blot 1:5000-1:20000
• Application Notes: This antibody is useful in ELISA and Western Blot.

Reactivity Notes

Human.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20mM Potassium Phosphate (pH 7.0) and 0.15M NaCl
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Notes

Manufactured by SDIX's proprietary Genomic Antibody Technology™. GAT FAQs.

Alternate Names for Aminopeptidase A/ENPEP Antibody

• Aminopeptidase A
• APA
• AP-A
• CD249 antigen
• CD249
• Differentiation antigen gp160
• EAP
• EC 3.4.11
• EC 3.4.11.7
• ENPEP
• glutamyl aminopeptidase (aminopeptidase A)
• glutamyl aminopeptidase
• gp160

Background

Aminopeptidase A is a zinc-dependent metallopeptidase that selectively cleaves N-terminal Glu, or Asp residues from peptides. In mice, it is expressed on early B cells and on a subset of thymic cortical epithelial cells, but not on mature lymphocytes. Additionally, it is expressed on endothelial cells, intestinal epithelium, proximal renal tubules, and other non-hemopoietic tissues. In humans, angiotensin II is the the best-defined biologically active substrate of APA. Although its role in the immune response is still uncertain, its expression on renal cell carcinoma has been the focus of some cancer research studies.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Aminopeptidase A/ENPEP Antibody (43180002)(2)

Publications using 43180002

• Garrison C, Lastwika K, Zhang Y et al. Proteomic Analysis, Immune Dysregulation, and Pathway Interconnections With Obesity J Proteome Res. 2017-01-06 [PMID: 27769113] (MiAr)
  
  Details:
  Analysis is performed on plasma proteomic data to identify how obesity can alter pathways and to highlight the risk factor for disease in subjects with a high body mass index.
• Rho JH, Lampe PD. High-throughput screening for native autoantigen-autoantibody complexes using antibody microarrays J Proteome Res. 2013-05-03 [PMID: 23541305] (MiAr)
  
  Details:
  A novel method using antibody microarrays is used to detect autoantibody-antigen complexes that can potentially be useful for detection and characterization of diseases.

Review for Aminopeptidase A/ENPEP Antibody (43180002) (1)

Average Rating: 4

(Based on 1 review)

We have 1 review tested in 1 species: Human.

reviewed by: Verified Customer MiAr Human 12/18/2018

Summary

• Application: Microarray
• Sample Tested: EDTA Plasma
• Species: Human
• Lot: T01535A01

Bioinformatics

• Gene Symbol: ENPEP
• Entrez:
  • 2028(Human)
• Uniprot:
  • Q07075(Human)