alpha Adaptin Antibody

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Western Blot: alpha Adaptin Antibody [NBP1-68949] - Human Brain lysate, concentration 0.2-1 ug/ml.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

alpha Adaptin Antibody Summary

Immunogen
Synthetic peptides corresponding to AP2A1 (adaptor-related protein complex 2, alpha 1 subunit) The peptide sequence was selected from the C terminal of AP2A1. Peptide sequence ILAKLKRKKGPGAGSALDDGRRDPSSNDINGGMEPTPSTVSTPSPSADLL.
Specificity
This product is specific to Subunit or Isofrom: alpha-1.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
AP2A1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
Application Notes
This is a rabbit polyclonal antibody against AP2A1 and was validated on Western blot.
Theoretical MW
105 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS and 2% Sucrose
Preservative
0.09% Sodium Azide
Purity
Immunogen affinity purified

Notes

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Alternate Names for alpha Adaptin Antibody

  • 100 kDa coated vesicle protein A
  • Adapter-related protein complex 2 alpha-1 subunit
  • Adaptor protein complex AP-2 subunit alpha-1
  • adaptor-related protein complex 2, alpha 1 subunit
  • ADTAAAP2-ALPHA
  • alpha1-adaptin
  • Alpha-adaptin A
  • AP-2 complex subunit alpha-1
  • CLAPA1adaptin, alpha A
  • Clathrin assembly protein complex 2 alpha-A large chain
  • clathrin-associated/assembly/adaptor protein, large, alpha 1
  • Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit

Background

This gene encodes the alpha 1 adaptin subunit of the adaptor protein 2 (AP-2) complex found in clathrin coated vesicles. The AP-2 complex is a heterotetramer consisting of two large adaptins (alpha or beta), a medium adaptin (mu), and a small adaptin (sigma). The complex is part of the protein coat on the cytoplasmic face of coated vesicles which links clathrin to receptors in vesicles. Alternative splicing of this gene results in two transcript variants encoding two different isoforms. A third transcript variant has been described, but its full length nature has not been determined.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol AP2A1